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          • Home
          • › Search Tool
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          • › Mm00446973_m1
          See other TBP GE Assays ›
          Gene Symbol:
          Tbp
          Gene Name:
          TATA box binding protein
          Gene Aliases:
          GTF2D1, Gtf2d, SCA17, TFIID
          Chromosome Location:
          Chr.17: 15499888 - 15517427 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm00446973_m1
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (31)

          Genomic Map

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          Assay Details

          Gene Symbol: Tbp
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_013684.3 NP_038712.3 4 - 5 768 73
          GenBank mRNA BC012685.1 - 6 - 7 1004 3498542 73
          BC016476.1 - 4 - 5 746 3584341 73
          BC050136.1 - 4 - 5 719 30020603 73
          D01034.1 - 3 - 4 585 73
          U63933.1 - 5 - 6 774 73

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          More Information


          Updated Mapping Information

          This assay targets the same location as MTA transcript cluster(s) TC1700000183.mm.1

          Set Membership:

          Ambion siRNA available Amplicon length between 71 and 85 Mammalian Gene Collection Endogenous Controls Mus musculus Mouse Endogenous Controls Inventoried Mouse_Endogenous_Controls Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Tbp

          Panther Classification:

          Molecular Function -

          general transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          transcription, DNA-templated
          DNA-templated transcription, initiation
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          transcription from RNA polymerase III promoter
          positive regulation of transcription, DNA-templated
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          RNA polymerase II repressing transcription factor binding
          DNA binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          transcription factor binding
          enzyme binding
          transcription regulatory region DNA binding
          repressing transcription factor binding

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          Citations (31)

          NPM-ALK-dependent expression of the transcription factor CCAAT/enhancer binding protein beta in ALK-positive anaplastic large cell lymphoma.
          Authors
          Quintanilla-Martinez L, Pittaluga S, Miething C, Klier M, Rudelius M, Davies-Hill T, Anastasov N, Martinez A, Vivero A, Duyster J, Jaffe ES, Fend F, Raffeld M
          Journal
          Blood - Page No 2029 (Fri Sep 15 00:00:00 EDT 2006)
          Volume (Year)
          108 (2006)
          Product Usage
          -
          Governing cell lineage formation in cloned mouse embryos.
          Authors
          Balbach ST, Esteves TC, Brink T, Gentile L, McLaughlin KJ, Adjaye JA, Boiani M
          Journal
          Dev Biol - Page No 71 (Thu Jul 01 00:00:00 EDT 2010)
          Volume (Year)
          343 (2010)
          Product Usage
          -
          Development of lupus nephritis is associated with qualitative changes in the glomerular collagen IV matrix composition.
          Authors
          Tveita AA, Ninomiya Y, Sado Y, Rekvig OP, Zykova SN
          Journal
          Lupus - Page No 355 (Wed Apr 01 00:00:00 EDT 2009)
          Volume (Year)
          18 (2009)
          Product Usage
          -
          A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis.
          Authors
          Sher RB, Aoyama C, Huebsch KA, Ji S, Kerner J, Yang Y, Frankel WN, Hoppel CL, Wood PA, Vance DE, Cox GA
          Journal
          J Biol Chem - Page No 4938 (Fri Feb 24 00:00:00 EST 2006)
          Volume (Year)
          281 (2006)
          Product Usage
          -
          Liver X receptor agonism promotes articular inflammation in murine collagen-induced arthritis.
          Authors
          Asquith DL, Miller AM, Hueber AJ, McKinnon HJ, Sattar N, Graham GJ, McInnes IB
          Journal
          Arthritis Rheum - Page No 2655 (Tue Sep 01 00:00:00 EDT 2009)
          Volume (Year)
          60 (2009)
          Product Usage
          -
          IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination.
          Authors
          Freude S, Leeser U, Muller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Kohler C, Schroder H, Krone W, Bruning JC, Schubert M
          Journal
          J Neurochem - Page No 907 (Sat Nov 01 00:00:00 EDT 2008)
          Volume (Year)
          107 (2008)
          Product Usage
          -
          Expression analysis of 6p22 genomic gain in retinoblastoma.
          Authors
          Orlic M, Spencer CE, Wang L, Gallie BL
          Journal
          Genes Chromosomes Cancer - Page No 72 (Sun Jan 01 00:00:00 EST 2006)
          Volume (Year)
          45 (2006)
          Product Usage
          -
          Deposition of chromatin-IgG complexes in skin of nephritic MRL-lpr/lpr mice is associated with increased local matrix metalloprotease activities.
          Authors
          Hedberg A, Fismen S, Fenton KA, Mortensen ES, Rekvig OP
          Journal
          Exp Dermatol - Page No e265 (Sun Aug 01 00:00:00 EDT 2010)
          Volume (Year)
          19 (2010)
          Product Usage
          -
          Anti-dsDNA antibodies promote initiation, and acquired loss of renal Dnase1 promotes progression of lupus nephritis in autoimmune (NZBxNZW)F1 mice.
          Authors
          Fenton K, Fismen S, Hedberg A, Seredkina N, Fenton C, Mortensen ES, Rekvig OP
          Journal
          Plos One - Page No e8474 (Thu Jan 01 00:00:00 EST 2009)
          Volume (Year)
          4 (2009)
          Product Usage
          -
          Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders.
          Authors
          Mercader JM, Saus E, Aguera Z, Bayes M, Boni C, Carreras A, Cellini E, de Cid R, Dierssen M, Escaramis G, Fernandez-Aranda F, Forcano L, Gallego X, Gonzalez JR, Gorwood P, Hebebrand J, Hinney A, Nacmias B, Puig A, Ribases M, Ricca V, Romo L, Sorbi S, Versini A, Gratacos M, Estivill X
          Journal
          Hum Mol Genet - Page No 1234 (Thu May 01 00:00:00 EDT 2008)
          Volume (Year)
          17 (2008)
          Product Usage
          -
          In vivo characterization of estrogen receptor modulators with reduced genomic versus nongenomic activity in vitro.
          Authors
          Otto C, Fuchs I, Altmann H, Klewer M, Schwarz G, Bohlmann R, Nguyen D, Zorn L, Vonk R, Prelle K, Osterman T, Malmstrom C, Fritzemeier KH
          Journal
          J Steroid Biochem Mol Biol - Page No 95 (Tue Jul 01 00:00:00 EDT 2008)
          Volume (Year)
          111 (2008)
          Product Usage
          -
          Metabolic bioactivation of oestradiol-17beta (E2beta) in mouse colon epithelial cells bearing ApcMin mutation.
          Authors
          Bellocq D, Molina J, Rathahao-Paris E, Tache S, Pierre F, Paris A
          Journal
          Steroids - Page No 665 (Fri Oct 01 00:00:00 EDT 2010)
          Volume (Year)
          75 (2010)
          Product Usage
          -
          Oxidised LDL up-regulate CD36 expression by the Nrf2 pathway in 3T3-L1 preadipocytes.
          Authors
          D'Archivio M, Scazzocchio B, Filesi C, Vari R, Maggiorella MT, Sernicola L, Santangelo C, Giovannini C, Masella R
          Journal
          Febs Lett - Page No 2291 (Wed Jun 25 00:00:00 EDT 2008)
          Volume (Year)
          582 (2008)
          Product Usage
          -
          Palifermin mediates immunoregulatory effects in addition to its cytoprotective effects in mice with acute graft-versus-host disease.
          Authors
          Ellison CA, Makar BM, Wiseman JM, Gheorghiu I, Taniguchi M, Gartner JG
          Journal
          J Clin Immunol - Page No 600 (Mon Sep 01 00:00:00 EDT 2008)
          Volume (Year)
          28 (2008)
          Product Usage
          -
          Cooperative role of NF-{kappa}B and poly(ADP-ribose) polymerase 1 (PARP-1) in the TNF-induced inhibition of PHEX expression in osteoblasts.
          Authors
          Majewski PM, Thurston RD, Ramalingam R, Kiela PR, Ghishan FK
          Journal
          J Biol Chem - Page No 34828 (Fri Nov 05 00:00:00 EDT 2010)
          Volume (Year)
          285 (2010)
          Product Usage
          -
          Microarray analysis of gene expression of mouse hepatocytes of different ploidy.
          Authors
          Lu P, Prost S, Caldwell H, Tugwood JD, Betton GR, Harrison DJ
          Journal
          Mamm Genome - Page No 617 (Sat Sep 01 00:00:00 EDT 2007)
          Volume (Year)
          18 (2007)
          Product Usage
          -
          An insulator embedded in the chicken {alpha}-globin locus regulates chromatin domain configuration and differential gene expression.
          Authors
          Furlan-Magaril M, Rebollar E, Guerrero G, Fernandez A, Molto E, Gonzalez-Buendia E, Cantero M, Montoliu L, Recillas-Targa F
          Journal
          Nucleic Acids Res - Page No (Thu Sep 02 00:00:00 EDT 2010)
          Volume (Year)
           (2010)
          Product Usage
          -
          Identification of mutations from phenotype-driven ENU mutagenesis in mouse chromosome 7.
          Authors
          Culiat CT, Klebig ML, Liu Z, Monroe H, Stanford B, Desai J, Tandan S, Hughes L, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Li Q
          Journal
          Mamm Genome - Page No 555 (Mon Aug 01 00:00:00 EDT 2005)
          Volume (Year)
          16 (2005)
          Product Usage
          -
          Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic mice.
          Authors
          Sasaki R, Nishimura N, Hoshino H, Isa Y, Kadowaki M, Ichi T, Tanaka A, Nishiumi S, Fukuda I, Ashida H, Horio F, Tsuda T
          Journal
          Biochem Pharmacol - Page No 1619 (Mon Dec 03 00:00:00 EST 2007)
          Volume (Year)
          74 (2007)
          Product Usage
          -
          Increased entropy production in diaphragm muscle of PPAR alpha knockout mice.
          Authors
          Lecarpentier Y, Krokidis X, Martin P, Pineau T, Hebert JL, Quillard J, Cortes-Morichetti M, Coirault C
          Journal
          J Theor Biol - Page No 92 (Mon Jan 07 00:00:00 EST 2008)
          Volume (Year)
          250 (2008)
          Product Usage
          -
          Synaptic organization in cochlear inner hair cells deficient for the CaV1.3 (alpha1D) subunit of L-type Ca2+ channels.
          Authors
          Nemzou N RM, Bulankina AV, Khimich D, Giese A, Moser T
          Journal
          Neuroscience - Page No 1849 (Fri Sep 15 00:00:00 EDT 2006)
          Volume (Year)
          141 (2006)
          Product Usage
          -
          Alpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization.
          Authors
          Kurz A, Wohr M, Walter M, Bonin M, Auburger G, Gispert S, Schwarting RK
          Journal
          Neuroscience - Page No 785 (Wed Mar 31 00:00:00 EDT 2010)
          Volume (Year)
          166 (2010)
          Product Usage
          -
          Maturation of ribbon synapses in hair cells is driven by thyroid hormone.
          Authors
          Sendin G, Bulankina AV, Riedel D, Moser T
          Journal
          J Neurosci - Page No 3163 (Wed Mar 21 00:00:00 EDT 2007)
          Volume (Year)
          27 (2007)
          Product Usage
          -
          The neuronal ceroid lipofuscinosis Cln8 gene expression is developmentally regulated in mouse brain and up-regulated in the hippocampal kindling model of epilepsy.
          Authors
          Lonka L, Aalto A, Kopra O, Kuronen M, Kokaia Z, Saarma M, Lehesjoki AE
          Journal
          Bmc Neurosci - Page No 27 (Sat Jan 01 00:00:00 EST 2005)
          Volume (Year)
          6 (2005)
          Product Usage
          -
          Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models.
          Authors
          Svec J, Ergang P, Mandys V, Kment M, Pacha J
          Journal
          Int J Exp Pathol - Page No 44 (Mon Feb 01 00:00:00 EST 2010)
          Volume (Year)
          91 (2010)
          Product Usage
          -
          Protocatechuic acid induces antioxidant/detoxifying enzyme expression through JNK-mediated Nrf2 activation in murine macrophages.
          Authors
          Vari R, D'Archivio M, Filesi C, Carotenuto S, Scazzocchio B, Santangelo C, Giovannini C, Masella R
          Journal
          J Nutr Biochem - Page No (Fri Jul 09 00:00:00 EDT 2010)
          Volume (Year)
           (2010)
          Product Usage
          -
          Comparative analysis of the uterine and mammary gland effects of drospirenone and medroxyprogesterone acetate.
          Authors
          Otto C, Fuchs I, Altmann H, Klewer M, Walter A, Prelle K, Vonk R, Fritzemeier KH
          Journal
          Endocrinology - Page No 3952 (Fri Aug 01 00:00:00 EDT 2008)
          Volume (Year)
          149 (2008)
          Product Usage
          -
          Corticosterone impairs dendritic cell maturation and function.
          Authors
          Elftman MD, Norbury CC, Bonneau RH, Truckenmiller ME
          Journal
          Immunology - Page No 279 (Mon Oct 01 00:00:00 EDT 2007)
          Volume (Year)
          122 (2007)
          Product Usage
          -
          Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression.
          Authors
          Alavian KN, Sgado P, Alberi L, Subramaniam S, Simon HH
          Journal
          Neural Dev - Page No 11 (Thu Jan 01 00:00:00 EST 2009)
          Volume (Year)
          4 (2009)
          Product Usage
          -
          Comparative in silico analysis identifies bona fide MyoD binding sites within the Myocyte stress 1 gene promoter.
          Authors
          Ounzain S, Dacwag CS, Samani NJ, Imbalzano AN, Chong NW
          Journal
          Bmc Mol Biol - Page No 50 (Tue Jan 01 00:00:00 EST 2008)
          Volume (Year)
          9 (2008)
          Product Usage
          -
          Attainment of brown adipocyte features in white adipocytes of hormone-sensitive lipase null mice.
          Authors
          Strom K, Hansson O, Lucas S, Nevsten P, Fernandez C, Klint C, Moverare-Skrtic S, Sundler F, Ohlsson C, Holm C
          Journal
          Plos One - Page No e1793 (Tue Jan 01 00:00:00 EST 2008)
          Volume (Year)
          3 (2008)
          Product Usage
          -

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