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          • › Search Tool
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          • › Mm00488369_s1
          See other SOX2 GE Assays ›
          Gene Symbol:
          Sox2
          Gene Name:
          SRY (sex determining region Y)-box 2
          Gene Aliases:
          Sox-2, lcc, ysb
          Chromosome Location:
          Chr.3: 34650005 - 34652461 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm00488369_s1
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (1)

          Genomic Map

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          Assay Details

          Gene Symbol: Sox2
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_011443.3 NP_035573.3 1 960 68
          GenBank mRNA AB108673.1 - 1 582 68
          AB221649.1 - 1 549 68
          AK131933.1 - 1 398 68
          AK149358.1 - 1 283 68
          BC057574.1 - 1 831 6413283 68
          U31967.1 - 1 910 68

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          More Information


          Updated Mapping Information

          This assay targets the same location as MTA transcript cluster(s) TC0300000244.mm.1

          Set Membership:

          Ambion siRNA available Amplicon length less than or equal to 70 Mammalian Gene Collection Detect Genomic DNA Mus musculus Mouse Stem Cell Pluripotency Inventoried Mouse_Stem_Cell Both primers and probe map within a single exon

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Sox2

          Panther Classification:

          Molecular Function -

          HMG box transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          osteoblast differentiation
          cell fate specification
          endodermal cell fate specification
          positive regulation of neuroblast proliferation
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          transcription from RNA polymerase II promoter
          cell cycle arrest
          multicellular organism development
          sensory perception of sound
          response to organic substance
          regulation of gene expression
          stem cell population maintenance
          forebrain neuron differentiation
          adenohypophysis development
          cerebral cortex development
          positive regulation of cell-cell adhesion
          negative regulation of Wnt signaling pathway
          male genitalia development
          positive regulation of epithelial cell differentiation
          olfactory placode formation
          response to retinoic acid
          somatic stem cell population maintenance
          inner ear morphogenesis
          regulation of cysteine-type endopeptidase activity involved in apoptotic process
          positive regulation of MAPK cascade
          tongue development
          cell fate commitment
          negative regulation of cell differentiation
          positive regulation of cell differentiation
          negative regulation of neuron differentiation
          positive regulation of neuron differentiation
          negative regulation of osteoblast differentiation
          positive regulation of Notch signaling pathway
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          pigment biosynthetic process
          lung alveolus development
          embryonic organ development
          anatomical structure formation involved in morphogenesis
          neuron fate commitment
          diencephalon morphogenesis
          stem cell differentiation
          negative regulation of epithelial cell proliferation
          regulation of neurogenesis
          detection of mechanical stimulus involved in sensory perception of sound
          detection of mechanical stimulus involved in equilibrioception
          retina morphogenesis in camera-type eye
          lens induction in camera-type eye
          epithelial tube branching involved in lung morphogenesis
          response to growth factor
          negative regulation of canonical Wnt signaling pathway
          neuronal stem cell population maintenance
          transcription regulatory region sequence-specific DNA binding
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          DNA binding
          chromatin binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          transcription factor binding
          chromatin DNA binding
          miRNA binding
          sequence-specific DNA binding
          transcription regulatory region DNA binding
          protein heterodimerization activity

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Mouse Clariom S Array PSR0300001583.mm.1 NM_011443.4 Refseq
          Affymetrix Mouse Clariom S Array PSR0300001583.mm.1 TC0300000244.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0300001585.mm.1 NM_011443.4 Refseq
          Affymetrix Mouse Clariom S Array PSR0300001585.mm.1 TC0300000244.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0300001584.mm.1 NM_011443.4 Refseq
          Affymetrix Mouse Clariom S Array PSR0300001584.mm.1 TC0300000244.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0300001586.mm.1 NM_011443.4 Refseq
          Affymetrix Mouse Clariom S Array PSR0300001586.mm.1 TC0300000244.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0300001587.mm.1 NM_011443.4 Refseq
          Affymetrix Mouse Clariom S Array PSR0300001587.mm.1 TC0300000244.mm.1 MTA TC

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          Citations (1)

          Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells.
          Authors
          Cole MF, Johnstone SE, Newman JJ, Kagey MH, Young RA
          Journal
          Genes Dev - Page No 746 (Sat Mar 15 00:00:00 EDT 2008)
          Volume (Year)
          22 (2008)
          Product Usage
          -

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