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          • › Search Tool
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          • › Mm00839704_mH
          See other FOXA2 GE Assays ›
          Gene Symbol:
          Foxa2
          Gene Name:
          forkhead box A2
          Gene Aliases:
          HNF3-beta, HNF3beta, Hnf-3b, Hnf3b, Tcf-3b, Tcf3b
          Chromosome Location:
          Chr.2: 148042877 - 148046969 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm00839704_mH
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (2)

          Genomic Map

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          Assay Details

          Gene Symbol: Foxa2
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_001291065.1 NP_001277994.1 1 - 2 124 64
          NM_010446.3 NP_034576.2 2 - 3 182 64
          GenBank mRNA AB231453.1 - 1 - 2 76 64
          CF948812.1 - 1 - 2 57 64
          L10409.1 - 1 - 2 83 64
          X74937.1 - 2 - 3 182 64

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          More Information


          Updated Mapping Information

          This assay targets the same location as MTA transcript cluster(s) TC0200004802.mm.1

          Set Membership:

          Ambion siRNA available Amplicon length less than or equal to 70 Mus musculus Inventoried Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Foxa2

          Panther Classification:

          Molecular Function -

          winged helix/forkhead transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          positive regulation of transcription from RNA polymerase II promoter by glucose
          negative regulation of transcription from RNA polymerase II promoter by glucose
          in utero embryonic development
          ectoderm formation
          cell fate specification
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          transcription from RNA polymerase II promoter
          Notch signaling pathway
          multicellular organism development
          pattern specification process
          adult locomotory behavior
          anatomical structure morphogenesis
          anterior/posterior pattern specification
          dorsal/ventral pattern formation
          regulation of gene expression
          negative regulation of epithelial to mesenchymal transition
          chromatin modification
          regulation of lipid metabolic process
          regulation of steroid metabolic process
          cell differentiation in hindbrain
          dorsal/ventral neural tube patterning
          signal transduction involved in regulation of gene expression
          regulation of blood coagulation
          lung development
          endocrine pancreas development
          somite rostral/caudal axis specification
          negative regulation of glucokinase activity
          positive regulation of embryonic development
          negative regulation of sequence-specific DNA binding transcription factor activity
          negative regulation of neuron differentiation
          positive regulation of neuron differentiation
          positive regulation of smoothened signaling pathway
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of transcription from RNA polymerase III promoter
          cell development
          anatomical structure formation involved in morphogenesis
          neuron fate specification
          epithelial tube branching involved in lung morphogenesis
          lung epithelial cell differentiation
          regulation of insulin secretion involved in cellular response to glucose stimulus
          connective tissue development
          response to interleukin-6
          dopaminergic neuron differentiation
          primitive streak formation
          positive regulation of gastrulation
          negative regulation of detection of glucose
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          DNA binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
          protein binding
          transcription factor binding
          kinase binding
          protein domain specific binding
          sequence-specific DNA binding
          transcription regulatory region DNA binding
          SMAD binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Mouse Clariom S Array PSR0200041033.mm.1 NM_010446.3 Refseq
          Affymetrix Mouse Clariom S Array PSR0200041033.mm.1 TC0200004802.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0200041042.mm.1 NM_010446.3 Refseq
          Affymetrix Mouse Clariom S Array PSR0200041042.mm.1 TC0200004802.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0200041034.mm.1 NM_010446.3 Refseq
          Affymetrix Mouse Clariom S Array PSR0200041034.mm.1 TC0200004802.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0200041041.mm.1 NM_010446.3 Refseq
          Affymetrix Mouse Clariom S Array PSR0200041041.mm.1 TC0200004802.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0200041035.mm.1 NM_010446.3 Refseq
          Affymetrix Mouse Clariom S Array PSR0200041035.mm.1 TC0200004802.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0200041037.mm.1 NM_010446.3 Refseq
          Affymetrix Mouse Clariom S Array PSR0200041037.mm.1 TC0200004802.mm.1 MTA TC

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          Citations (2)

          Foxa2 programs Th2 cell-mediated innate immunity in the developing lung.
          Authors
          Chen G, Wan H, Luo F, Zhang L, Xu Y, Lewkowich I, Wills-Karp M, Whitsett JA
          Journal
          J Immunol - Page No 6133 (Tue Jun 01 00:00:00 EDT 2010)
          Volume (Year)
          184 (2010)
          Product Usage
          -
          Fibroblast growth factor 21 corrects obesity in mice.
          Authors
          Coskun T, Bina HA, Schneider MA, Dunbar JD, Hu CC, Chen Y, Moller DE, Kharitonenkov A
          Journal
          Endocrinology - Page No 6018 (Mon Dec 01 00:00:00 EST 2008)
          Volume (Year)
          149 (2008)
          Product Usage
          -

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