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          • Home
          • › Search Tool
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          • › Rn00572010_m1
          See other TGFB1 GE Assays ›
          Gene Symbol:
          Tgfb1
          Gene Name:
          transforming growth factor, beta 1
          Gene Aliases:
          Tgfb
          Chromosome Location:
          Chr.1: 82480875 - 82497196 on Build Rnor_6.0
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          Assay ID Rn00572010_m1
          Best Coverage
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (2)

          Genomic Map

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          Assay Details

          Gene Symbol: Tgfb1
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_021578.2 NP_067589.1 1 - 2 500 65
          GenBank mRNA AY550025.1 - 1 - 2 355 65
          BC076380.1 - 1 - 2 500 7107411 65
          X52498.1 - 1 - 2 767 65

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          More Information


          Updated Mapping Information

          This assay targets the same location as RTA transcript cluster(s) TC0100008028.rn.1

          Set Membership:

          Ambion siRNA available Amplicon length less than or equal to 70 Mammalian Gene Collection Recommended Assay Rattus norvegicus Rat Chemokine Panel Rat Tumor Metastasis Panel Inventoried Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Tgfb1

          Panther Classification:

          Molecular Function -

          growth factor

          Gene Ontology Categories:

          Function(s) Process(es)

          protein import into nucleus, translocation
          negative regulation of transcription from RNA polymerase II promoter
          MAPK cascade
          regulation of cell growth
          ureteric bud development
          response to hypoxia
          morphogenesis of a branching structure
          cell activation
          epithelial to mesenchymal transition
          negative regulation of protein phosphorylation
          positive regulation of protein phosphorylation
          regulation of sodium ion transport
          chondrocyte differentiation
          hematopoietic progenitor cell differentiation
          adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
          tolerance induction to self antigen
          protein phosphorylation
          protein export from nucleus
          ATP biosynthetic process
          phosphate-containing compound metabolic process
          cellular calcium ion homeostasis
          inflammatory response
          cell cycle arrest
          mitotic cell cycle checkpoint
          epidermal growth factor receptor signaling pathway
          transforming growth factor beta receptor signaling pathway
          common-partner SMAD protein phosphorylation
          SMAD protein complex assembly
          SMAD protein import into nucleus
          negative regulation of neuroblast proliferation
          salivary gland morphogenesis
          endoderm development
          female pregnancy
          aging
          negative regulation of DNA replication
          cell proliferation
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          germ cell migration
          response to radiation
          response to wounding
          response to glucose
          defense response to fungus, incompatible interaction
          response to organic substance
          positive regulation of gene expression
          negative regulation of gene expression
          positive regulation of epithelial to mesenchymal transition
          positive regulation of fibroblast migration
          positive regulation of peptidyl-threonine phosphorylation
          positive regulation of pathway-restricted SMAD protein phosphorylation
          negative regulation of macrophage cytokine production
          response to organic cyclic compound
          cell growth
          regulation of striated muscle tissue development
          regulation of transforming growth factor beta receptor signaling pathway
          evasion or tolerance of host defenses by virus
          negative regulation of cell-cell adhesion
          hyaluronan catabolic process
          T cell differentiation
          negative regulation of ossification
          negative regulation of cell growth
          lung development
          positive regulation of cell migration
          positive regulation of bone mineralization
          mammary gland development
          positive regulation of histone deacetylation
          organ regeneration
          positive regulation of protein complex assembly
          positive regulation of exit from mitosis
          lipopolysaccharide-mediated signaling pathway
          positive regulation of cellular protein metabolic process
          response to estradiol
          response to progesterone
          positive regulation of interleukin-17 production
          receptor catabolic process
          positive regulation of superoxide anion generation
          mononuclear cell proliferation
          positive regulation of collagen biosynthetic process
          positive regulation of peptidyl-serine phosphorylation
          response to vitamin D
          response to laminar fluid shear stress
          positive regulation of histone acetylation
          positive regulation of protein dephosphorylation
          wound healing
          T cell activation
          regulation of cell proliferation
          negative regulation of T cell proliferation
          regulation of protein import into nucleus
          positive regulation of protein import into nucleus
          positive regulation of odontogenesis
          response to drug
          myelination
          myeloid dendritic cell differentiation
          T cell homeostasis
          positive regulation of apoptotic process
          positive regulation of MAP kinase activity
          regulation of MAPK cascade
          protein kinase B signaling
          positive regulation of blood vessel endothelial cell migration
          negative regulation of blood vessel endothelial cell migration
          positive regulation of phosphatidylinositol 3-kinase activity
          ossification involved in bone remodeling
          regulatory T cell differentiation
          cell-cell junction organization
          negative regulation of fat cell differentiation
          negative regulation of myoblast differentiation
          negative regulation of cell cycle
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          negative regulation of mitotic cell cycle
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of isotype switching to IgA isotypes
          lymph node development
          digestive tract development
          negative regulation of skeletal muscle tissue development
          inner ear development
          positive regulation of epithelial cell proliferation
          negative regulation of epithelial cell proliferation
          positive regulation of protein secretion
          negative regulation of phagocytosis
          negative regulation of immune response
          negative regulation of T cell activation
          positive regulation of chemotaxis
          positive regulation of NF-kappaB transcription factor activity
          regulation of binding
          regulation of DNA binding
          positive regulation of smooth muscle cell differentiation
          negative regulation of release of sequestered calcium ion into cytosol
          positive regulation of protein kinase B signaling
          face morphogenesis
          frontal suture morphogenesis
          pathway-restricted SMAD protein phosphorylation
          positive regulation of SMAD protein import into nucleus
          SMAD protein signal transduction
          mammary gland branching involved in thelarche
          branch elongation involved in mammary gland duct branching
          regulation of branching involved in mammary gland duct morphogenesis
          negative regulation of gene silencing by miRNA
          regulation of cartilage development
          lens fiber cell differentiation
          response to cholesterol
          positive regulation of cell cycle arrest
          cellular response to growth factor stimulus
          cellular response to organic cyclic compound
          cellular response to dexamethasone stimulus
          cellular response to transforming growth factor beta stimulus
          extracellular matrix assembly
          positive regulation of branching involved in ureteric bud morphogenesis
          extrinsic apoptotic signaling pathway
          negative regulation of hyaluronan biosynthetic process
          positive regulation of protein localization to nucleus
          positive regulation of NAD+ ADP-ribosyltransferase activity
          regulation of actin cytoskeleton reorganization
          regulation of miRNA metabolic process
          positive regulation of transcription regulatory region DNA binding
          glycoprotein binding
          antigen binding
          type II transforming growth factor beta receptor binding
          cytokine activity
          transforming growth factor beta receptor binding
          growth factor activity
          enzyme binding
          type I transforming growth factor beta receptor binding
          type III transforming growth factor beta receptor binding
          protein homodimerization activity
          protein heterodimerization activity
          protein N-terminus binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Rat Clariom S Assay PSR0100065064.rn.1 TC0100008028.rn.1 RTA TC
          Affymetrix Rat Clariom S Assay PSR0100065065.rn.1 TC0100008028.rn.1 RTA TC

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          Citations (2)

          Effects of a new bioactive lipid-based drug carrier on cultured hepatic stellate cells and liver fibrosis in bile duct-ligated rats.
          Authors
          Adrian JE, Poelstra K, Scherphof GL, Meijer DK, van Loenen-Weemaes AM, Reker-Smit C, Morselt HW, Zwiers P, Kamps JA
          Journal
          J Pharmacol Exp Ther - Page No 536 (Tue May 01 00:00:00 EDT 2007)
          Volume (Year)
          321 (2007)
          Product Usage
          -
          Early postnatal oestradiol exposure causes insulin resistance and signs of inflammation in circulation and skeletal muscle.
          Authors
          Alexanderson C, Eriksson E, Stener-Victorin E, Lonn M, Holmang A
          Journal
          J Endocrinol - Page No 49 (Wed Apr 01 00:00:00 EDT 2009)
          Volume (Year)
          201 (2009)
          Product Usage
          -

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