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          • Home
          • › Search Tool
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          • › Rn00675535_m1
          See other LYN GE Assays ›
          Gene Symbol:
          Lyn
          Gene Name:
          LYN proto-oncogene, Src family tyrosine kinase
          Gene Aliases:
          p53Lyn, p56Lyn
          Chromosome Location:
          Chr.5: 16526058 - 16642648 on Build Rnor_6.0
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          Assay ID Rn00675535_m1
          Best Coverage
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Gene Symbol: Lyn
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_001111098.1 NP_001104568.1 10 - 11 1212 60
          NM_030857.2 NP_110484.1 10 - 11 1275 60
          XM_006237834.2 XP_006237896.1 10 - 11 1591 60
          GenBank mRNA AF000300.1 - 10 - 11 1120 60
          AF000301.1 - 10 - 11 1212 60
          AF000302.1 - 10 - 11 1210 60
          L14782.1 - 9 - 10 1069 60
          L14823.1 - 9 - 10 1006 60
          L14951.1 - 10 - 11 1278 60

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          More Information


          Updated Mapping Information

          This assay targets the same location as RTA transcript cluster(s) TC0500000129.rn.1

          Set Membership:

          Ambion siRNA available Amplicon length less than or equal to 70 Recommended Assay Rattus norvegicus 1700 Inventoried Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Lyn

          Gene Ontology Categories:

          Function(s) Process(es)

          B cell homeostasis
          cytokine production
          regulation of cytokine production
          negative regulation of protein phosphorylation
          Fc receptor mediated stimulatory signaling pathway
          tolerance induction to self antigen
          histamine secretion by mast cell
          platelet degranulation
          negative regulation of myeloid leukocyte differentiation
          immune response-regulating cell surface receptor signaling pathway
          Fc receptor mediated inhibitory signaling pathway
          regulation of B cell apoptotic process
          protein phosphorylation
          chemotaxis
          cellular response to DNA damage stimulus
          response to sterol depletion
          transmembrane receptor protein tyrosine kinase signaling pathway
          positive regulation of cell population proliferation
          negative regulation of cell population proliferation
          response to xenobiotic stimulus
          response to toxic substance
          response to hormone
          response to carbohydrate
          positive regulation of neuron projection development
          oligodendrocyte development
          response to organic cyclic compound
          cell migration
          peptidyl-tyrosine phosphorylation
          hemopoiesis
          erythrocyte differentiation
          positive regulation of cell migration
          negative regulation of B cell proliferation
          neuron projection development
          lipopolysaccharide-mediated signaling pathway
          cellular response to extracellular stimulus
          response to insulin
          regulation of mast cell activation
          regulation of cell adhesion mediated by integrin
          negative regulation of toll-like receptor 2 signaling pathway
          negative regulation of toll-like receptor 4 signaling pathway
          cellular response to heat
          intracellular signal transduction
          peptidyl-tyrosine autophosphorylation
          positive regulation of phosphorylation
          positive regulation of tyrosine phosphorylation of STAT protein
          response to amino acid
          regulation of mast cell degranulation
          negative regulation of MAP kinase activity
          response to peptide hormone
          positive regulation of phosphatidylinositol 3-kinase activity
          innate immune response
          regulation of erythrocyte differentiation
          protein autophosphorylation
          response to axon injury
          regulation of inflammatory response
          positive regulation of peptidyl-tyrosine phosphorylation
          B cell receptor signaling pathway
          regulation of B cell receptor signaling pathway
          positive regulation of B cell receptor signaling pathway
          positive regulation of cellular component movement
          regulation of release of sequestered calcium ion into cytosol
          positive regulation of glial cell proliferation
          positive regulation of Fc receptor mediated stimulatory signaling pathway
          positive regulation of stress-activated protein kinase signaling cascade
          regulation of ERK1 and ERK2 cascade
          negative regulation of ERK1 and ERK2 cascade
          positive regulation of oligodendrocyte progenitor proliferation
          negative regulation of mast cell proliferation
          positive regulation of mast cell proliferation
          cellular response to retinoic acid
          cellular response to peptide hormone stimulus
          regulation of monocyte chemotaxis
          regulation of platelet aggregation
          dendritic cell differentiation
          negative regulation of intracellular signal transduction
          positive regulation of dendritic cell apoptotic process
          protein kinase activity
          protein tyrosine kinase activity
          non-membrane spanning protein tyrosine kinase activity
          signaling receptor binding
          platelet-derived growth factor receptor binding
          integrin binding
          protein binding
          ATP binding
          kinase activity
          SH3 domain binding
          enzyme binding
          ubiquitin protein ligase binding
          gamma-tubulin binding
          glycosphingolipid binding
          transmembrane transporter binding
          protein-containing complex binding
          phosphoprotein binding

          MicroArray Probes:

          Affymetrix ABI

          Array Name Probe IDs Targets Target Type
          Affymetrix Rat Clariom S Assay PSR0500000883.rn.1 TC0500000129.rn.1 RTA TC
          Array Name Probe IDs Targets Target Type
          ABI Rat Genome Survey Microarray 22295169 - -

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