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          System Message

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          See other ISL1 SIRNA Assays ›
          Gene Symbol:
          ISL1
          Gene Name:
          ISL LIM homeobox 1
          Gene Aliases:
          ISLET1, Isl-1
          Chromosome Location:
          Chr.5: 51383124 - 51394730 on Build GRCh38
          UniGene ID:
          Hs.505
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 115272

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ISL1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_002202.2 NP_002193.2 6 1833
          XM_011543380.2 XP_011541682.1 5 2951
          GenBank mRNA BC031213.1 - 6 1834 5269369
          U07559.1 - 6 1524

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          neural crest cell migration
          secondary heart field specification
          outflow tract septum morphogenesis
          outflow tract morphogenesis
          endocardial cushion morphogenesis
          cardiac right ventricle morphogenesis
          regulation of secondary heart field cardioblast proliferation
          regulation of transcription from RNA polymerase II promoter
          transcription from RNA polymerase II promoter
          positive regulation of cell proliferation
          positive regulation of vascular endothelial growth factor production
          spinal cord motor neuron cell fate specification
          spinal cord motor neuron differentiation
          visceral motor neuron differentiation
          trigeminal nerve development
          pituitary gland development
          pancreas development
          axon regeneration
          retinal ganglion cell axon guidance
          positive regulation of insulin secretion
          positive regulation of granulocyte macrophage colony-stimulating factor production
          positive regulation of interferon-gamma production
          positive regulation of interleukin-1 alpha production
          positive regulation of interleukin-1 beta production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-6 production
          positive regulation of tumor necrosis factor production
          negative regulation of intracellular estrogen receptor signaling pathway
          positive regulation of histone acetylation
          positive regulation of tyrosine phosphorylation of Stat3 protein
          positive regulation of DNA binding
          negative regulation of neuron apoptotic process
          negative regulation of neuron differentiation
          positive regulation of angiogenesis
          positive regulation of transcription from RNA polymerase II promoter
          neuron fate specification
          mesenchymal cell differentiation
          sensory system development
          peripheral nervous system neuron axonogenesis
          negative regulation of inflammatory response
          ventricular cardiac muscle tissue morphogenesis
          pharyngeal system development
          cardiac muscle cell myoblast differentiation
          innervation
          atrial septum morphogenesis
          cardiac cell fate determination
          cellular response to glucocorticoid stimulus
          positive regulation of granulocyte colony-stimulating factor production
          negative regulation of protein homodimerization activity
          negative regulation of canonical Wnt signaling pathway
          positive regulation of macrophage colony-stimulating factor production
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          RNA polymerase II activating transcription factor binding
          RNA polymerase II transcription coactivator activity
          enhancer sequence-specific DNA binding
          chromatin binding
          protein binding
          zinc ion binding
          ligand-dependent nuclear receptor binding
          estrogen receptor binding
          bHLH transcription factor binding

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