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          System Message

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          LOADING ...
          See other EIF2AK3 SIRNA Assays ›
          Gene Symbol:
          Eif2ak3
          Gene Name:
          eukaryotic translation initiation factor 2 alpha kinase 3
          Gene Aliases:
          AI427929, Pek, Perk
          Chromosome Location:
          Chr.6: 70844484 - 70905240 on Build GRCm38
          UniGene ID:
          Mm.247167
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 158368

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Eif2ak3
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_010121.2 NP_034251.2 4, 5 950
          GenBank mRNA AF076681.1 - 4, 5 942
          AK139679.1 - 2, 3 272
          BC054809.1 - 4, 5 962 6839221

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_031599, XM_006236624, XM_006236623, XM_008762977, AF096835.

          Gene Ontology Categories:

          Function(s) Process(es)

          skeletal system development
          ossification
          angiogenesis
          chondrocyte development
          translation
          regulation of translation
          protein phosphorylation
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          ER overload response
          response to unfolded protein
          endoplasmic reticulum organization
          lactation
          positive regulation of signal transduction
          positive regulation of vascular endothelial growth factor production
          positive regulation of gene expression
          negative regulation of gene expression
          regulation of translational initiation by eIF2 alpha phosphorylation
          phosphorylation
          negative regulation of translation
          peptidyl-serine phosphorylation
          regulation of fatty acid metabolic process
          calcium-mediated signaling
          bone mineralization
          endoplasmic reticulum unfolded protein response
          pancreas development
          endocrine pancreas development
          negative regulation of myelination
          negative regulation of translation in response to stress
          positive regulation of protein binding
          SREBP signaling pathway
          response to endoplasmic reticulum stress
          PERK-mediated unfolded protein response
          cellular response to glucose starvation
          negative regulation of apoptotic process
          fat cell differentiation
          positive regulation of transcription from RNA polymerase I promoter
          protein autophosphorylation
          insulin-like growth factor receptor signaling pathway
          protein homooligomerization
          intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
          positive regulation of protein localization to nucleus
          negative regulation of translation in response to endoplasmic reticulum stress
          regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          positive regulation of glutathione biosynthetic process
          positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
          nucleotide binding
          protein kinase activity
          protein serine/threonine kinase activity
          eukaryotic translation initiation factor 2alpha kinase activity
          protein binding
          ATP binding
          kinase activity
          transferase activity
          transferase activity, transferring phosphorus-containing groups
          enzyme binding
          protein phosphatase binding
          identical protein binding
          Hsp90 protein binding
          eukaryotic initiation factor eIF2 binding

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