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          System Message

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          See other DRD2 SIRNA Assays ›
          Gene Symbol:
          DRD2
          Gene Name:
          dopamine receptor D2
          Gene Aliases:
          D2DR, D2R
          Chromosome Location:
          Chr.11: 113409595 - 113475279 on Build GRCh38
          UniGene ID:
          Hs.73893
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 1835

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: DRD2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000795.3 NP_000786.1 3 554
          NM_016574.3 NP_057658.2 3 554
          XM_017017296.1 XP_016872785.1 3 536
          GenBank mRNA AB209832.1 - 2 349
          AB451480.1 - 2 319
          AF176812.1 - 2 328
          AK308777.1 - 3 384
          BC021195.2 - 3 414 3939741
          BF437994.1 - 3 386
          M29066.1 - 2 352
          M30625.1 - 3 655
          S62137.1 - 2 636
          S69899.1 - 3 418
          X51362.1 - 3 484
          X51645.1 - 2 347

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_012547, XM_006242979, XM_008766190, XM_008766191, X56065, and others.
          This siRNA also targets the following transcripts in Mouse: NM_010077, BC105666, X55674, BC105665, BC105664, and others.

          Set Membership:

          G-protein coupled receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          temperature homeostasis
          response to hypoxia
          synaptic transmission, dopaminergic
          response to amphetamine
          neurological system process involved in regulation of systemic arterial blood pressure
          regulation of heart rate
          regulation of sodium ion transport
          G-protein coupled receptor internalization
          positive regulation of neuroblast proliferation
          positive regulation of receptor internalization
          negative regulation of adenylate cyclase activity
          adenylate cyclase-inhibiting dopamine receptor signaling pathway
          neuron-neuron synaptic transmission
          axonogenesis
          synapse assembly
          sensory perception of smell
          long-term memory
          grooming behavior
          locomotory behavior
          adult walking behavior
          feeding behavior
          protein localization
          negative regulation of cell proliferation
          associative learning
          visual learning
          response to light stimulus
          response to toxic substance
          response to iron ion
          regulation of dopamine secretion
          response to inactivity
          Wnt signaling pathway
          striatum development
          orbitofrontal cortex development
          cerebral cortex GABAergic interneuron migration
          adenohypophysis development
          negative regulation of cell migration
          peristalsis
          regulation of cAMP metabolic process
          auditory behavior
          activation of protein kinase activity
          regulation of synaptic transmission, GABAergic
          positive regulation of cytokinesis
          circadian regulation of gene expression
          negative regulation of dopamine secretion
          response to histamine
          response to nicotine
          positive regulation of urine volume
          positive regulation of renal sodium excretion
          positive regulation of multicellular organism growth
          response to cocaine
          negative regulation of circadian sleep/wake cycle, sleep
          dopamine metabolic process
          response to drug
          regulation of potassium ion transport
          response to morphine
          pigmentation
          regulation of phosphoprotein phosphatase activity
          positive regulation of G-protein coupled receptor protein signaling pathway
          negative regulation of blood pressure
          negative regulation of innate immune response
          positive regulation of transcription from RNA polymerase II promoter
          phosphatidylinositol metabolic process
          negative regulation of insulin secretion
          acid secretion
          behavioral response to cocaine
          behavioral response to ethanol
          regulation of long-term neuronal synaptic plasticity
          response to axon injury
          branching morphogenesis of a nerve
          arachidonic acid secretion
          negative regulation of protein secretion
          release of sequestered calcium ion into cytosol
          negative regulation of cytosolic calcium ion concentration
          regulation of dopamine uptake involved in synaptic transmission
          positive regulation of dopamine uptake involved in synaptic transmission
          regulation of synapse structural plasticity
          negative regulation of protein kinase B signaling
          negative regulation of synaptic transmission, glutamatergic
          positive regulation of growth hormone secretion
          prepulse inhibition
          phospholipase C-activating dopamine receptor signaling pathway
          negative regulation of dopamine receptor signaling pathway
          positive regulation of ERK1 and ERK2 cascade
          adenylate cyclase-activating adrenergic receptor signaling pathway
          regulation of locomotion involved in locomotory behavior
          chemical synaptic transmission, postsynaptic
          positive regulation of glial cell-derived neurotrophic factor secretion
          positive regulation of long-term synaptic potentiation
          negative regulation of voltage-gated calcium channel activity
          dopamine neurotransmitter receptor activity, coupled via Gi/Go
          adrenergic receptor activity
          protein binding
          drug binding
          dopamine binding
          ionotropic glutamate receptor binding
          identical protein binding
          protein homodimerization activity
          protein heterodimerization activity

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          git-commit: 2310f86ea667df8f532fad8d69a2d0b8b05e2a1e
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