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          System Message

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          See other SMAD4 SIRNA Assays ›
          Gene Symbol:
          Smad4
          Gene Name:
          SMAD family member 4
          Gene Aliases:
          Madh4
          Chromosome Location:
          Chr.18: 69627824 - 69657301 on Build Rnor_6.0
          UniGene ID:
          Rn.9774
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          siRNA ID 50871

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Smad4
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_019275.2 NP_062148.1 4 541
          GenBank mRNA AB010954.1 - 4 541
          AF056002.1 - 613

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          branching involved in ureteric bud morphogenesis
          response to hypoxia
          in utero embryonic development
          gastrulation with mouth forming second
          kidney development
          atrioventricular valve formation
          epithelial to mesenchymal transition involved in endocardial cushion formation
          positive regulation of cell proliferation involved in heart valve morphogenesis
          cardiac septum development
          brainstem development
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          transcription from RNA polymerase II promoter
          transforming growth factor beta receptor signaling pathway
          SMAD protein complex assembly
          gastrulation
          axon guidance
          endoderm development
          mesoderm development
          cell proliferation
          negative regulation of cell proliferation
          anterior/posterior pattern specification
          positive regulation of epithelial to mesenchymal transition
          positive regulation of pathway-restricted SMAD protein phosphorylation
          neural crest cell differentiation
          regulation of transforming growth factor beta receptor signaling pathway
          negative regulation of cell growth
          BMP signaling pathway
          positive regulation of transforming growth factor beta receptor signaling pathway
          positive regulation of BMP signaling pathway
          somite rostral/caudal axis specification
          regulation of transforming growth factor beta2 production
          intracellular signal transduction
          atrioventricular canal development
          endothelial cell activation
          regulation of cell proliferation
          negative regulation of protein catabolic process
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          developmental growth
          neuron fate commitment
          tissue morphogenesis
          sebaceous gland development
          formation of anatomical boundary
          regulation of binding
          regulation of hair follicle development
          palate development
          positive regulation of SMAD protein import into nucleus
          SMAD protein signal transduction
          negative regulation of cell death
          endocardial cell differentiation
          response to transforming growth factor beta
          metanephric mesenchyme morphogenesis
          nephrogenic mesenchyme morphogenesis
          RNA polymerase II regulatory region sequence-specific DNA binding
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          core promoter proximal region sequence-specific DNA binding
          transcription factor activity, RNA polymerase II transcription factor binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          RNA polymerase II transcription factor binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          DNA binding
          chromatin binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          collagen binding
          transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
          filamin binding
          identical protein binding
          protein homodimerization activity
          sequence-specific DNA binding
          transcription regulatory region DNA binding
          SMAD binding
          metal ion binding
          protein heterodimerization activity
          I-SMAD binding
          R-SMAD binding

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