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          System Message

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          LOADING ...
          See other APC SIRNA Assays ›
          Gene Symbol:
          Apc
          Gene Name:
          adenomatosis polyposis coli
          Gene Aliases:
          AI047805, AU020952, AW124434, CC1, Min, mAPC
          Chromosome Location:
          Chr.18: 34220307 - 34322190 on Build GRCm38
          UniGene ID:
          Mm.384171
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 59993

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Apc
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_007462.3 NP_031488.2 2, 3 439
          GenBank mRNA AK042021.1 - 2, 3 440
          AK045053.1 - 2, 3 410
          AK046280.1 - 2, 3 430
          AK080907.1 - 2, 3 439
          AK082724.1 - 2, 3 185
          BC141141.1 - 1, 2 152 9055753
          M88127.1 - 1, 2 128

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Human: NM_000038, NM_001127510, DA795663, DA777787, M74088, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          mitotic cytokinesis
          kidney development
          hair follicle development
          protein complex assembly
          cellular response to DNA damage stimulus
          negative regulation of microtubule depolymerization
          cell cycle arrest
          metaphase/anaphase transition of mitotic cell cycle
          mitotic spindle assembly checkpoint
          establishment or maintenance of cell polarity
          pattern specification process
          axonogenesis
          negative regulation of cell proliferation
          axis specification
          anterior/posterior pattern specification
          dorsal/ventral pattern formation
          proximal/distal pattern formation
          Wnt signaling pathway
          cell migration
          stem cell population maintenance
          negative regulation of Wnt signaling pathway
          regulation of cell migration
          positive regulation of cell migration
          regulation of epithelial cell differentiation
          positive regulation of epithelial cell differentiation
          positive regulation of microtubule polymerization
          cytoplasmic microtubule organization
          neuron projection development
          positive regulation of pseudopodium assembly
          regulation of microtubule-based process
          T cell differentiation in thymus
          somatic stem cell population maintenance
          negative regulation of odontogenesis
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          negative regulation of MAPK cascade
          skin development
          canonical Wnt signaling pathway involved in negative regulation of apoptotic process
          canonical Wnt signaling pathway involved in positive regulation of apoptotic process
          regulation of cell differentiation
          positive regulation of cell differentiation
          regulation of osteoblast differentiation
          regulation of osteoclast differentiation
          positive regulation of protein catabolic process
          negative regulation of cyclin-dependent protein serine/threonine kinase activity
          positive regulation of cell adhesion
          muscle cell cellular homeostasis
          thymus development
          negative regulation of epithelial cell proliferation
          regulation of nitrogen compound metabolic process
          chromosome organization
          regulation of cell cycle
          positive regulation of cell division
          regulation of attachment of spindle microtubules to kinetochore
          retina development in camera-type eye
          canonical Wnt signaling pathway
          negative regulation of epithelial cell proliferation involved in prostate gland development
          negative regulation of canonical Wnt signaling pathway
          regulation of glutamate metabolic process
          protease binding
          protein binding
          beta-catenin binding
          microtubule binding
          protein kinase regulator activity
          protein kinase binding
          protein complex binding
          gamma-catenin binding
          microtubule plus-end binding

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