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          System Message

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          LOADING ...
          See other APP SIRNA Assays ›
          Gene Symbol:
          App
          Gene Name:
          amyloid beta (A4) precursor protein
          Gene Aliases:
          Abeta, Abpp, Adap, Ag, Cvap, E030013M08Rik, betaApp
          Chromosome Location:
          Chr.16: 84954436 - 85173952 on Build GRCm38
          UniGene ID:
          Mm.277585
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 60180

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: App
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001198823.1 NP_001185752.1 11, 12 1614
          NM_001198824.1 NP_001185753.1 10, 11 1557
          NM_001198825.1 NP_001185754.1 10, 11 1557
          NM_001198826.1 NP_001185755.1 11, 12 1614
          NM_007471.3 NP_031497.2 9, 10 1389
          GenBank mRNA AK029172.1 - 1, 2 2782
          AK076506.1 - 3, 4 309
          AK128971.1 - 10, 11 1566
          AK133639.1 - 10, 11 1554
          AK147543.1 - 9, 10 1425
          AK148439.1 - 11, 12 1487
          AK159245.1 - 11, 12 1623
          AK159352.1 - 11, 12 1620
          AK159718.1 - 11, 12 1600
          AK161854.1 - 4, 5 471
          AK161976.1 - 9, 10 1364
          AY267348.1 - 11, 12 1465
          BC005490.1 - 7, 8 978
          BC070409.1 - 9, 10 1385 5708093
          M18373.1 - 9, 10 1378
          U84012.1 - 9, 10 1378
          X59379.1 - 9, 10 1308

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_019288, XM_006248010, XM_006248009, XM_006248011, XM_006248008, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          suckling behavior
          mRNA polyadenylation
          regulation of translation
          protein phosphorylation
          cellular copper ion homeostasis
          endocytosis
          apoptotic process
          response to oxidative stress
          cell adhesion
          regulation of epidermal growth factor-activated receptor activity
          Notch signaling pathway
          nervous system development
          axonogenesis
          mating behavior
          locomotory behavior
          axo-dendritic transport
          cholesterol metabolic process
          adult locomotory behavior
          visual learning
          negative regulation of peptidase activity
          regulation of gene expression
          negative regulation of endopeptidase activity
          positive regulation of peptidase activity
          positive regulation of G2/M transition of mitotic cell cycle
          axon midline choice point recognition
          neuron remodeling
          dendrite development
          extracellular matrix organization
          forebrain development
          neuron projection development
          ionotropic glutamate receptor signaling pathway
          regulation of multicellular organism growth
          regulation of protein binding
          negative regulation of neuron differentiation
          positive regulation of mitotic cell cycle
          positive regulation of transcription from RNA polymerase II promoter
          collateral sprouting in absence of injury
          regulation of synapse structure or activity
          neuromuscular process controlling balance
          synaptic growth at neuromuscular junction
          protein homooligomerization
          neuron apoptotic process
          smooth endoplasmic reticulum calcium ion homeostasis
          DNA binding
          serine-type endopeptidase inhibitor activity
          receptor binding
          protein binding
          heparin binding
          peptidase activator activity
          enzyme binding
          peptidase inhibitor activity
          acetylcholine receptor binding
          identical protein binding
          metal ion binding
          transition metal ion binding
          PTB domain binding
          growth factor receptor binding

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