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          System Message

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          See other PTPN6 SIRNA Assays ›
          Gene Symbol:
          Ptpn6
          Gene Name:
          protein tyrosine phosphatase, non-receptor type 6
          Gene Aliases:
          70Z-SHP, Hcph, PTPTY-42, Ptp1C, SH-PTP1, SHP-1, hcp, me
          Chromosome Location:
          Chr.6: 124720707 - 124738709 on Build GRCm38
          UniGene ID:
          Mm.271799
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 71198

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Ptpn6
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001077705.2 NP_001071173.1 15 1930
          NM_013545.3 NP_038573.2 15 1928
          GenBank mRNA AK132509.1 - 15 1847
          AK150509.1 - 15 1835
          AK151077.1 - 15 1849
          AK151623.1 - 15 1852
          AK159686.1 - 15 1888
          AK159833.1 - 15 1881
          AK167923.1 - 15 1882
          AK169804.1 - 15 1930
          BC012660.1 - 15 1873 4010462
          M68902.1 - 15 1880
          M90389.1 - 15 1830

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_053908, BC099824, U77038, FQ232747, AF468653.

          Gene Ontology Categories:

          Function(s) Process(es)

          hematopoietic progenitor cell differentiation
          negative regulation of humoral immune response mediated by circulating immunoglobulin
          protein dephosphorylation
          signal transduction
          cell proliferation
          positive regulation of cell proliferation
          positive regulation of phosphatidylinositol 3-kinase signaling
          dephosphorylation
          peptidyl-tyrosine phosphorylation
          cytokine-mediated signaling pathway
          cell differentiation
          platelet formation
          abortive mitotic cell cycle
          positive regulation of cell adhesion mediated by integrin
          peptidyl-tyrosine dephosphorylation
          intracellular signal transduction
          megakaryocyte development
          negative regulation of T cell proliferation
          natural killer cell mediated cytotoxicity
          negative regulation of MAP kinase activity
          negative regulation of MAPK cascade
          regulation of B cell differentiation
          negative regulation of peptidyl-tyrosine phosphorylation
          B cell receptor signaling pathway
          negative regulation of B cell receptor signaling pathway
          negative regulation of T cell receptor signaling pathway
          regulation of release of sequestered calcium ion into cytosol
          regulation of ERK1 and ERK2 cascade
          platelet aggregation
          regulation of G1/S transition of mitotic cell cycle
          phosphotyrosine binding
          phosphoprotein phosphatase activity
          protein tyrosine phosphatase activity
          transmembrane receptor protein tyrosine phosphatase activity
          protein binding
          hydrolase activity
          phosphatase activity
          SH3 domain binding
          protein kinase binding
          SH2 domain binding
          natural killer cell lectin-like receptor binding

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