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          System Message

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          LOADING ...
          See other ESR1 SIRNA Assays ›
          Gene Symbol:
          ESR1
          Gene Name:
          estrogen receptor 1
          Gene Aliases:
          ER, ESR, ESRA, ESTRR, Era, NR3A1
          Chromosome Location:
          Chr.6: 151654148 - 152103274 on Build GRCh38
          UniGene ID:
          Hs.208124
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS103377
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ESR1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000125.3 NP_000116.2 7 1689
          NM_001122740.1 NP_001116212.1 8 1716
          NM_001122741.1 NP_001116213.1 8 1673
          NM_001122742.1 NP_001116214.1 9 1825
          NM_001291230.1 NP_001278159.1 8 1679
          NM_001291241.1 NP_001278170.1 8 1670
          XM_006715375.3 XP_006715438.1 7 1822
          XM_011535543.2 XP_011533845.1 10 3650
          XM_011535544.2 XP_011533846.1 8 1834
          XM_011535545.2 XP_011533847.1 8 1723
          XM_011535549.2 XP_011533851.1 5 836
          XM_017010376.1 XP_016865865.1 9 4272
          XM_017010377.1 XP_016865866.1 10 4331
          XM_017010378.1 XP_016865867.1 9 1783
          XM_017010379.1 XP_016865868.1 9 1817
          XM_017010380.1 XP_016865869.1 8 4141
          XM_017010381.1 XP_016865870.1 8 1569
          XM_017010382.1 XP_016865871.1 6 889
          XM_017010383.1 XP_016865872.1 5 1194
          GenBank mRNA AB307713.1 - 7 1455
          AF258449.1 - 4 1021
          AF258450.1 - 3 904
          AF258451.1 - 4 783
          AK293019.1 - 8 1638
          AK304833.1 - 8 1496
          AK313644.1 - 8 1647
          BC128573.1 - 7 1560 40128594
          BC128574.1 - 7 1560 40128595
          EU921455.1 - 2 150
          FJ011559.1 - 2 131
          FJ147552.1 - 5 336
          FJ169500.1 - 2 105
          FJ169503.1 - 5 395
          FJ716812.1 - 3 244
          GQ389792.1 - 2 95
          GQ411258.1 - 5 540
          GQ438791.1 - 2 63
          JF810888.1 - 7 1455
          LC120329.1 - 7 1664
          M12674.1 - 7 1747
          U47678.1 - 1455
          X03635.1 - 7 1815
          Z75126.1 - 4 398

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: AK041525, AB560758, AF128221, AK077236, EU791538, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          antral ovarian follicle growth
          osteoblast development
          chromatin remodeling
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          transcription initiation from RNA polymerase II promoter
          signal transduction
          phospholipase C-activating G-protein coupled receptor signaling pathway
          positive regulation of cytosolic calcium ion concentration
          androgen metabolic process
          negative regulation of gene expression
          positive regulation of phospholipase C activity
          intracellular steroid hormone receptor signaling pathway
          intracellular estrogen receptor signaling pathway
          response to estradiol
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of sequence-specific DNA binding transcription factor activity
          regulation of neuron apoptotic process
          response to estrogen
          positive regulation of epidermal growth factor receptor signaling pathway
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of glucose import
          decidualization
          positive regulation of fibroblast proliferation
          negative regulation of smooth muscle cell proliferation
          positive regulation of epithelial cell proliferation
          positive regulation of sequence-specific DNA binding transcription factor activity
          Sertoli cell development
          Sertoli cell proliferation
          uterus development
          vagina development
          prostate epithelial cord elongation
          prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
          regulation of branching involved in prostate gland morphogenesis
          mammary gland branching involved in pregnancy
          mammary gland alveolus development
          epithelial cell proliferation involved in mammary gland duct elongation
          positive regulation of ERK1 and ERK2 cascade
          protein localization to chromatin
          cellular response to estrogen stimulus
          cellular response to estradiol stimulus
          negative regulation of triglyceride metabolic process
          negative regulation of neuron death
          negative regulation of production of miRNAs involved in gene silencing by miRNA
          baculum development
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          core promoter sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          transcription coactivator binding
          chromatin binding
          transcription factor activity, sequence-specific DNA binding
          steroid hormone receptor activity
          steroid binding
          protein binding
          beta-catenin binding
          transcription factor binding
          zinc ion binding
          enzyme binding
          nitric-oxide synthase regulator activity
          estrogen receptor activity
          type 1 metabotropic glutamate receptor binding
          protein complex binding
          estrogen response element binding
          phosphatidylinositol 3-kinase regulatory subunit binding
          RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
          hormone binding
          identical protein binding
          ATPase binding

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          Host server : magellan-search-74594944d-pk6zc:80/100.66.130.62:80.
          git-commit: ab2b2261c2971e97b1ae408e3ad10520b8413932
          git-url: https://github.com/thermofisher/magellan-search
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