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          System Message

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          LOADING ...
          See other TP53 SIRNA Assays ›
          Gene Symbol:
          TP53
          Gene Name:
          tumor protein p53
          Gene Aliases:
          BCC7, LFS1, P53, TRP53
          Chromosome Location:
          Chr.17: 7668402 - 7687550 on Build GRCh38
          UniGene ID:
          Hs.437460
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS110905
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: TP53
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000546.5 NP_000537.3 10 1222
          NM_001126112.2 NP_001119584.1 10 1219
          NM_001126113.2 NP_001119585.1 11 1282
          NM_001126114.2 NP_001119586.1 11 1355
          NM_001126115.1 NP_001119587.1 6 902
          NM_001126116.1 NP_001119588.1 7 1035
          NM_001126117.1 NP_001119589.1 7 962
          NM_001126118.1 NP_001119590.1 9 1339
          NM_001276695.1 NP_001263624.1 11 1282
          NM_001276696.1 NP_001263625.1 11 1355
          NM_001276697.1 NP_001263626.1 6 902
          NM_001276698.1 NP_001263627.1 7 1035
          NM_001276699.1 NP_001263628.1 7 962
          NM_001276760.1 NP_001263689.1 10 1222
          NM_001276761.1 NP_001263690.1 10 1219
          GenBank mRNA AB082923.1 - 10 1083
          AF307851.1 - 10 1155
          AK223026.1 - 4 315
          AK225838.1 - 10 1160
          AK297462.1 - 11 1087
          AK297927.1 - 11 1132
          AK312568.1 - 10 1164
          AM076970.1 - 9 987
          AY429684.1 - 9 1020
          BC003596.1 - 10 1140 3544714
          BT019622.1 - 9 1020
          DQ186648.1 - 11 1285
          DQ186649.1 - 11 1212
          DQ186650.1 - 6 898
          DQ186651.1 - 7 1031
          DQ186652.1 - 7 958
          DQ191317.1 - 10 1209
          DQ263704.1 - 9 1020
          DQ286964.1 - 10 1154
          DQ648886.1 - 2 96
          EF101867.1 - 9 987
          FJ207420.1 - 10 1155
          JN214348.1 - 9 1065
          JN601513.1 - 9 1020
          JN601514.1 - 9 1020
          JN601515.1 - 9 1020
          JN601516.1 - 10 994
          JN900492.1 - 9 1328
          JQ026207.1 - 9 1010
          JQ026208.1 - 9 1015
          JQ026209.1 - 9 1025
          JQ026210.1 - 9 1015
          JQ694049.1 - 9 1043
          JQ694050.1 - 9 1043
          JQ694051.1 - 9 1043
          M14694.1 - 10 1145
          M14695.1 - 10 1141
          X01405.1 - 7 721
          X02469.1 - 10 1155
          X60011.1 - 9 1020
          X60012.1 - 9 1020
          X60013.1 - 9 1020
          X60014.1 - 9 1020
          X60015.1 - 9 1020
          X60016.1 - 9 1020
          X60017.1 - 9 1020
          X60018.1 - 9 1020
          X60019.1 - 9 1020
          X60020.1 - 9 1020

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_030989, XM_006246594, XM_006246595, XM_003749209, XM_008767773, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          DNA strand renaturation
          base-excision repair
          nucleotide-excision repair
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          protein complex assembly
          cellular response to DNA damage stimulus
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
          ER overload response
          cell cycle arrest
          Ras protein signal transduction
          multicellular organism development
          cell aging
          protein localization
          cell proliferation
          negative regulation of cell proliferation
          determination of adult lifespan
          response to X-ray
          response to gamma radiation
          positive regulation of gene expression
          viral process
          protein sumoylation
          cell differentiation
          negative regulation of cell growth
          DNA damage response, signal transduction by p53 class mediator
          positive regulation of histone deacetylation
          chromatin assembly
          mitotic G1 DNA damage checkpoint
          positive regulation of protein oligomerization
          cellular response to UV
          cellular response to drug
          cellular response to glucose starvation
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          regulation of apoptotic process
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          entrainment of circadian clock by photoperiod
          proteasome-mediated ubiquitin-dependent protein catabolic process
          positive regulation of neuron apoptotic process
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          response to antibiotic
          positive regulation of protein export from nucleus
          regulation of mitochondrial membrane permeability
          negative regulation of fibroblast proliferation
          circadian behavior
          positive regulation of peptidyl-tyrosine phosphorylation
          negative regulation of helicase activity
          protein tetramerization
          negative regulation of telomerase activity
          positive regulation of thymocyte apoptotic process
          positive regulation of cell cycle arrest
          cellular response to hypoxia
          cellular response to ionizing radiation
          intrinsic apoptotic signaling pathway by p53 class mediator
          positive regulation of release of cytochrome c from mitochondria
          replicative senescence
          oxidative stress-induced premature senescence
          intrinsic apoptotic signaling pathway
          oligodendrocyte apoptotic process
          positive regulation of execution phase of apoptosis
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of signal transduction by p53 class mediator
          regulation of cell cycle G2/M phase transition
          positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
          positive regulation of reactive oxygen species metabolic process
          positive regulation of intrinsic apoptotic signaling pathway
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          core promoter sequence-specific DNA binding
          RNA polymerase II transcription factor binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          protease binding
          p53 binding
          DNA binding
          chromatin binding
          damaged DNA binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          copper ion binding
          protein binding
          ATP binding
          transcription factor binding
          zinc ion binding
          enzyme binding
          protein kinase binding
          protein phosphatase binding
          receptor tyrosine kinase binding
          ubiquitin protein ligase binding
          histone acetyltransferase binding
          identical protein binding
          sequence-specific DNA binding
          protein self-association
          transcription regulatory region DNA binding
          protein heterodimerization activity
          protein N-terminus binding
          chaperone binding
          protein phosphatase 2A binding

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          Host server : magellan-search-74594944d-pk6zc:80/100.66.130.62:80.
          git-commit: ab2b2261c2971e97b1ae408e3ad10520b8413932
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.31.0-2025.06.23-1.0