Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Cell Culture Media
    • Chemicals
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Greener Products
    • See all product categories
  • Applications
    • Bioprocessing
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Chromatography
    • Molecular Testing
    • Digital Solutions
    • DNA and RNA Extraction and Analysis
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • Custom Services
    • Enterprise Services
    • Financial and Leasing Services
    • Instrument Services
    • Lab Informatics
    • OEM and Commercial Supply
    • Training Services
    • Unity Lab Services
    • See all services
  • Help and Support
    • How to Order
    • Instrument Support
    • Learning Centers
    • Register for an Account
    • Technical Support Centers
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search Thermo Fisher Scientific

Search All
Search button Close
          • Order Status
          • Quick Order
          • Sign in
            Sign in
            Don't have an account ? Create Account
            • Account
            • Check Order Status
            • Aspire Member Program
            • Connect: Lab, Data, Apps
            • Custom Products & Projects
            • Services Central
          This product has been added to your favorites list. Go to My Favorites

          System Message

          OKCancel
          LOADING ...
          See other LEP SIRNA Assays ›
          Gene Symbol:
          LEP
          Gene Name:
          leptin
          Gene Aliases:
          LEPD, OB, OBS
          Chromosome Location:
          Chr.7: 128241201 - 128257629 on Build GRCh38
          UniGene ID:
          Hs.194236
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS180661
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

          LOADING...
          ×
          Back To Top

          siRNA Details

          Gene Symbol: LEP
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000230.2 NP_000221.1 2 177
          XM_005250340.4 XP_005250397.1 2 254
          GenBank mRNA AF008123.1 - 1 137
          AK313553.1 - 2 175
          BC060830.1 - 2 175 30333193
          BC069323.1 - 1 171 7262097
          BC069452.1 - 1 171 7262109
          BC069527.1 - 1 171 7262121
          D49487.1 - 1 137
          DA762132.1 - 2 177
          U18915.1 - 1 120
          U43653.1 - 1 176

          Back To Top

          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          angiogenesis
          ovulation from ovarian follicle
          response to hypoxia
          positive regulation of cytokine production
          placenta development
          regulation of endothelial cell proliferation
          response to dietary excess
          cardiac muscle hypertrophy
          glucose metabolic process
          regulation of gluconeogenesis
          energy reserve metabolic process
          glycerol biosynthetic process
          lipid metabolic process
          fatty acid beta-oxidation
          tyrosine phosphorylation of STAT protein
          female pregnancy
          circadian rhythm
          cholesterol metabolic process
          bile acid metabolic process
          regulation of blood pressure
          adult feeding behavior
          negative regulation of autophagy
          negative regulation of lipid storage
          positive regulation of phosphatidylinositol 3-kinase signaling
          response to activity
          sexual reproduction
          central nervous system neuron development
          insulin secretion
          T cell differentiation
          regulation of intestinal cholesterol absorption
          positive regulation of TOR signaling
          negative regulation of appetite
          prostaglandin secretion
          response to estradiol
          regulation of natural killer cell activation
          regulation of natural killer cell proliferation
          response to insulin
          response to vitamin E
          leptin-mediated signaling pathway
          positive regulation of luteinizing hormone secretion
          positive regulation of peroxisome proliferator activated receptor signaling pathway
          bone mineralization involved in bone maturation
          negative regulation of appetite by leptin-mediated signaling pathway
          positive regulation of T cell proliferation
          regulation of natural killer cell mediated cytotoxicity
          hormone metabolic process
          positive regulation of tyrosine phosphorylation of Stat3 protein
          glucose homeostasis
          eating behavior
          negative regulation of apoptotic process
          positive regulation of ion transport
          positive regulation of MAPK cascade
          cellular response to leptin stimulus
          response to ethanol
          positive regulation of myeloid cell differentiation
          regulation of angiogenesis
          negative regulation of vasoconstriction
          negative regulation of glucose import
          positive regulation of JAK-STAT cascade
          positive regulation of insulin receptor signaling pathway
          regulation of bone remodeling
          positive regulation of follicle-stimulating hormone secretion
          positive regulation of developmental growth
          regulation of insulin secretion
          regulation of steroid biosynthetic process
          intestinal absorption
          leukocyte tethering or rolling
          regulation of nitric-oxide synthase activity
          regulation of cell cycle
          positive regulation of protein kinase B signaling
          regulation of lipoprotein lipid oxidation
          adipose tissue development
          negative regulation of cartilage development
          negative regulation of glucagon secretion
          cellular response to L-ascorbic acid
          cellular response to retinoic acid
          interleukin-6 secretion
          interleukin-8 secretion
          regulation of brown fat cell differentiation
          bone growth
          regulation of cytokine production involved in inflammatory response
          positive regulation of p38MAPK cascade
          positive regulation of fat cell apoptotic process
          activation of protein kinase C activity
          positive regulation of STAT protein import into nucleus
          positive regulation of reactive oxygen species metabolic process
          negative regulation of glutamine transport
          positive regulation of hepatic stellate cell activation
          hormone activity
          growth factor activity
          peptide hormone receptor binding

          Back To Top

          Related Products

          • Anti-GAPDH, Mouse Monoclonal 6C5
          • Anti-β-Actin, Mouse Monoclonal AC-15
          • TaqMan® Gene Expression Cells-to-CT™
          • Neon™ Transfection System 100 µL Kit
          • Lipofectamine™ RNAiMAX Transfection Reagent
          • Invivofectamine 2.0
          • Lipofectamine™ 2000 Transfection Reagent
          • Neon™ Transfection System
          Ordering Plus Icon Minus Icon
          • Order Status
          • Order Help
          • Quick Order
          • Supply Center
          • eProcurement
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us
          • Technical Support Centers
          • Documents and Certificates
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Webinars
          • Social Media
          About Thermo Fisher Plus Icon Minus Icon
          • About Us
          • Careers
          • Investors
          • News
          • Social Responsibility
          • Trademarks
          • Consumer Health Data Privacy Policy
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Information Center
          • Price & Freight Policy
          © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          United States flag icon
          United States

          Your items have has been added!


          Host server : magellan-search-7b8d7ffddb-2cdg5:80/100.66.130.62:80.
          git-commit: 44eaffc35a31f29f64b20d0c2dd51bfa522c97f5
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.31.0-2025.06.23-1.0