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          System Message

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          LOADING ...
          See other PML SIRNA Assays ›
          Gene Symbol:
          PML
          Gene Name:
          promyelocytic leukemia
          Gene Aliases:
          MYL, PP8675, RNF71, TRIM19
          Chromosome Location:
          Chr.15: 73994673 - 74047819 on Build GRCh38
          UniGene ID:
          Hs.526464
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS182389
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PML
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_002675.3 NP_002666.1 3 1177
          NM_033238.2 NP_150241.2 3 1177
          NM_033239.2 NP_150242.1 3 1177
          NM_033240.2 NP_150243.2 3 1177
          NM_033244.3 NP_150247.2 3 1177
          NM_033246.2 NP_150249.1 3 1177
          NM_033247.2 NP_150250.2 3 1177
          NM_033249.2 NP_150252.1 3 1177
          NM_033250.2 NP_150253.2 3 1177
          GenBank mRNA AB208950.1 - 3 1047
          AB209051.1 - 2 888
          AB209411.1 - 3 1121
          AF230401.1 - 3 1109
          AF230402.1 - 3 1109
          AF230403.1 - 3 1109
          AF230404.1 - 3 1109
          AF230405.1 - 3 1109
          AF230406.1 - 3 1109
          AF230407.1 - 3 1109
          AF230408.1 - 3 1109
          AF230409.1 - 3 1109
          AF230410.1 - 3 1109
          AF230411.1 - 3 1109
          BC000080.2 - 3 1098 3506984
          BC020994.2 - 3 1098 2958462
          BC139795.1 - 1 155
          BT009911.1 - 3 1037
          M73778.1 - 3 1117
          M79462.1 - 3 1051
          M79463.1 - 3 1051
          M79464.1 - 3 1051
          M80185.1 - 3 1051
          S50913.1 - 3 1119
          X63131.1 - 3 1178

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          response to hypoxia
          regulation of protein phosphorylation
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          protein complex assembly
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          cell cycle arrest
          transforming growth factor beta receptor signaling pathway
          common-partner SMAD protein phosphorylation
          SMAD protein import into nucleus
          negative regulation of cell proliferation
          intrinsic apoptotic signaling pathway in response to oxidative stress
          response to UV
          response to gamma radiation
          regulation of calcium ion transport into cytosol
          fibroblast migration
          negative regulation of angiogenesis
          protein sumoylation
          myeloid cell differentiation
          regulation of cell adhesion
          negative regulation of cell growth
          PML body organization
          positive regulation of telomere maintenance
          endoplasmic reticulum calcium ion homeostasis
          circadian regulation of gene expression
          response to cytokine
          regulation of circadian rhythm
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          entrainment of circadian clock by photoperiod
          proteasome-mediated ubiquitin-dependent protein catabolic process
          innate immune response
          cell fate commitment
          regulation of MHC class I biosynthetic process
          negative regulation of transcription, DNA-templated
          positive regulation of fibroblast proliferation
          retinoic acid receptor signaling pathway
          negative regulation of interleukin-1 beta secretion
          maintenance of protein location in nucleus
          defense response to virus
          interferon-gamma-mediated signaling pathway
          branching involved in mammary gland duct morphogenesis
          intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
          cellular response to interleukin-4
          cellular senescence
          extrinsic apoptotic signaling pathway
          regulation of signal transduction by p53 class mediator
          negative regulation of viral release from host cell
          negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          regulation of double-strand break repair
          positive regulation of extrinsic apoptotic signaling pathway
          DNA binding
          protein binding
          zinc ion binding
          ubiquitin protein ligase binding
          SUMO binding
          protein homodimerization activity
          SMAD binding

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