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          System Message

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          LOADING ...
          See other SIRT2 SIRNA Assays ›
          Gene Symbol:
          Sirt2
          Gene Name:
          sirtuin 2
          Gene Aliases:
          5730427M03Rik, SIR2L2, Sir2l
          Chromosome Location:
          Chr.7: 28766752 - 28788665 on Build GRCm38
          UniGene ID:
          Mm.272443
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID MSS227069
          Size 20 nmol
          Availability Made To Order
          Catalog # 1320001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Sirt2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001122765.1 NP_001116237.1 5 412
          NM_001122766.1 NP_001116238.1 3 249
          NM_022432.4 NP_071877.3 6 459
          GenBank mRNA AB221570.1 - 6 364
          AF299337.1 - 6 444
          AK014042.1 - 5 383
          AK144431.1 - 5 355
          AK146412.1 - 5 392
          BB868649.1 - 3 214
          BC021439.1 - 6 463 5039278
          KF032392.1 - 6 401

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_001008368, XM_006228676, XM_006228675, XM_006228673, XM_006228672, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          protein deacetylation
          autophagy
          cell cycle
          mitotic nuclear division
          nervous system development
          negative regulation of cell proliferation
          negative regulation of autophagy
          negative regulation of peptidyl-threonine phosphorylation
          phosphatidylinositol 3-kinase signaling
          histone deacetylation
          myelination in peripheral nervous system
          cell differentiation
          regulation of myelination
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process
          cellular response to oxidative stress
          peptidyl-lysine deacetylation
          cellular response to hepatocyte growth factor stimulus
          negative regulation of protein catabolic process
          negative regulation of apoptotic process
          proteasome-mediated ubiquitin-dependent protein catabolic process
          positive regulation of DNA binding
          protein kinase B signaling
          cellular lipid catabolic process
          regulation of fat cell differentiation
          negative regulation of fat cell differentiation
          positive regulation of meiotic nuclear division
          negative regulation of striated muscle tissue development
          negative regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          hepatocyte growth factor receptor signaling pathway
          negative regulation of oligodendrocyte differentiation
          cell division
          meiotic cell cycle
          regulation of cell cycle
          positive regulation of cell division
          positive regulation of attachment of spindle microtubules to kinetochore
          negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
          cellular response to caloric restriction
          negative regulation of oligodendrocyte progenitor proliferation
          histone H3 deacetylation
          histone H4 deacetylation
          cellular response to molecule of bacterial origin
          cellular response to hypoxia
          cellular response to epinephrine stimulus
          tubulin deacetylation
          positive regulation of execution phase of apoptosis
          positive regulation of oocyte maturation
          negative regulation of NLRP3 inflammasome complex assembly
          negative regulation of defense response to bacterium
          ripoptosome assembly involved in necroptotic process
          negative regulation of reactive oxygen species metabolic process
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
          chromatin binding
          histone deacetylase activity
          protein binding
          transcription factor binding
          zinc ion binding
          protein-N-terminal asparagine amidohydrolase activity
          UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
          hydrolase activity
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
          iprodione amidohydrolase activity
          (3,5-dichlorophenylurea)acetate amidohydrolase activity
          protein deacetylase activity
          4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity
          didemethylisoproturon amidohydrolase activity
          N-isopropylacetanilide amidohydrolase activity
          N-cyclohexylformamide amidohydrolase activity
          isonicotinic acid hydrazide hydrolase activity
          cis-aconitamide amidase activity
          gamma-N-formylaminovinylacetate hydrolase activity
          NAD-dependent protein deacetylase activity
          histone acetyltransferase binding
          histone deacetylase binding
          tubulin deacetylase activity
          ubiquitin binding
          N2-acetyl-L-lysine deacetylase activity
          O-succinylbenzoate synthase activity
          indoleacetamide hydrolase activity
          N-acetylcitrulline deacetylase activity
          metal ion binding
          NAD-dependent histone deacetylase activity (H4-K16 specific)
          N-acetylgalactosamine-6-phosphate deacetylase activity
          beta-tubulin binding
          NAD binding
          diacetylchitobiose deacetylase activity
          chitooligosaccharide deacetylase activity
          NAD+ binding

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