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          System Message

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          LOADING ...
          See other SYK SIRNA Assays ›
          Gene Symbol:
          Syk
          Gene Name:
          spleen tyrosine kinase
          Gene Aliases:
          Sykb
          Chromosome Location:
          Chr.13: 52582329 - 52648792 on Build GRCm38
          UniGene ID:
          Mm.375031
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID MSS238075
          Size 20 nmol
          Availability Made To Order
          Catalog # 1320001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Syk
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001198977.1 NP_001185906.1 10 1493
          NM_011518.2 NP_035648.2 10 1497
          GenBank mRNA AK049207.1 - 10 1522
          AK136363.1 - 10 1496
          AK143564.1 - 10 1526
          BC065121.1 - 10 1429 30533300
          U25685.1 - 9 1281
          U36776.1 - 10 1500
          Z49877.1 - 10 1755

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_012758, U21684, U21683, L20838.

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPK activity
          angiogenesis
          serotonin secretion
          lymph vessel development
          adaptive immune response
          macrophage activation involved in immune response
          neutrophil activation involved in immune response
          leukocyte activation involved in immune response
          immune system process
          serotonin secretion by platelet
          protein phosphorylation
          leukocyte cell-cell adhesion
          cell surface receptor signaling pathway
          enzyme linked receptor protein signaling pathway
          transmembrane receptor protein tyrosine kinase signaling pathway
          G-protein coupled receptor signaling pathway
          integrin-mediated signaling pathway
          activation of JUN kinase activity
          regulation of platelet activation
          regulation of tumor necrosis factor-mediated signaling pathway
          phosphorylation
          cell migration
          peptidyl-serine phosphorylation
          peptidyl-tyrosine phosphorylation
          leukotriene biosynthetic process
          signal transduction by protein phosphorylation
          cell differentiation
          neutrophil chemotaxis
          regulation of superoxide anion generation
          positive regulation of cell adhesion mediated by integrin
          intracellular signal transduction
          peptidyl-tyrosine autophosphorylation
          defense response to bacterium
          transcription factor import into nucleus
          positive regulation of mast cell degranulation
          regulation of neutrophil degranulation
          beta selection
          innate immune response
          positive regulation of interleukin-3 biosynthetic process
          positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
          positive regulation of B cell differentiation
          positive regulation of gamma-delta T cell differentiation
          positive regulation of bone resorption
          positive regulation of alpha-beta T cell differentiation
          positive regulation of alpha-beta T cell proliferation
          protein autophosphorylation
          blood vessel morphogenesis
          positive regulation of cytokine secretion
          positive regulation of peptidyl-tyrosine phosphorylation
          regulation of phagocytosis
          regulation of immune response
          positive regulation of calcium-mediated signaling
          B cell receptor signaling pathway
          regulation of sequence-specific DNA binding transcription factor activity
          regulation of ERK1 and ERK2 cascade
          cellular response to molecule of fungal origin
          regulation of arachidonic acid secretion
          regulation of platelet aggregation
          nucleotide binding
          protein kinase activity
          protein serine/threonine kinase activity
          protein tyrosine kinase activity
          non-membrane spanning protein tyrosine kinase activity
          receptor signaling protein tyrosine kinase activity
          receptor binding
          integrin binding
          protein binding
          ATP binding
          kinase activity
          transferase activity
          transferase activity, transferring phosphorus-containing groups
          protein kinase binding
          protein domain specific binding

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