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          System Message

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          LOADING ...
          See other PTPN2 SIRNA Assays ›
          Gene Symbol:
          Ptpn2
          Gene Name:
          protein tyrosine phosphatase, non-receptor type 2
          Gene Aliases:
          -
          Chromosome Location:
          Chr.18: 63415298 - 63489266 on Build Rnor_6.0
          UniGene ID:
          Rn.33497
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          siRNA ID RSS300749
          Size 20 nmol
          Availability Made To Order
          Catalog # 1330001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Ptpn2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_053990.1 NP_446442.1 3 241
          XM_006254854.2 XP_006254916.1 3 1480
          XM_006254855.2 XP_006254917.1 3 1480
          XM_008772080.1 XP_008770302.1 3 1480
          XM_008772081.1 XP_008770303.1 3 1480
          GenBank mRNA BC078758.1 - 3 280 7132485
          X58828.1 - 3 241

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: NM_001127177, NM_008977, BC008269, AK076072, M80739, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          protein dephosphorylation
          negative regulation of cell proliferation
          insulin receptor signaling pathway
          negative regulation of tumor necrosis factor-mediated signaling pathway
          negative regulation of lipid storage
          B cell differentiation
          T cell differentiation
          erythrocyte differentiation
          peptidyl-tyrosine dephosphorylation
          negative regulation of epidermal growth factor receptor signaling pathway
          negative regulation of tyrosine phosphorylation of Stat1 protein
          negative regulation of tyrosine phosphorylation of Stat3 protein
          negative regulation of tyrosine phosphorylation of Stat5 protein
          negative regulation of tyrosine phosphorylation of Stat6 protein
          glucose homeostasis
          negative regulation of macrophage differentiation
          positive regulation of gluconeogenesis
          negative regulation of insulin receptor signaling pathway
          negative regulation of inflammatory response
          negative regulation of T cell receptor signaling pathway
          negative regulation of chemotaxis
          negative regulation of interferon-gamma-mediated signaling pathway
          negative regulation of type I interferon-mediated signaling pathway
          negative regulation of interleukin-6-mediated signaling pathway
          negative regulation of ERK1 and ERK2 cascade
          regulation of hepatocyte growth factor receptor signaling pathway
          negative regulation of interleukin-2-mediated signaling pathway
          negative regulation of prolactin signaling pathway
          negative regulation of interleukin-4-mediated signaling pathway
          negative regulation of macrophage colony-stimulating factor signaling pathway
          negative regulation of positive thymic T cell selection
          negative regulation of platelet-derived growth factor receptor-beta signaling pathway
          DNA binding
          protein tyrosine phosphatase activity
          non-membrane spanning protein tyrosine phosphatase activity
          integrin binding
          protein kinase binding
          syntaxin binding
          receptor tyrosine kinase binding

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          git-commit: 1827ea18100b76eacea45a9906e00cdefce2d263
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