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          System Message

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          LOADING ...
          See other ESR1 SIRNA Assays ›
          Gene Symbol:
          ESR1
          Gene Name:
          estrogen receptor 1
          Gene Aliases:
          ER, ESR, ESRA, ESTRR, Era, NR3A1
          Chromosome Location:
          Chr.6: 151654148 - 152103274 on Build GRCh38
          UniGene ID:
          Hs.208124
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID VHS40912
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ESR1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000125.3 NP_000116.2 6, 7 1603
          NM_001122740.1 NP_001116212.1 7, 8 1630
          NM_001122741.1 NP_001116213.1 7, 8 1587
          NM_001122742.1 NP_001116214.1 8, 9 1739
          NM_001291230.1 NP_001278159.1 7, 8 1593
          NM_001291241.1 NP_001278170.1 7, 8 1584
          XM_006715375.3 XP_006715438.1 6, 7 1736
          XM_011535543.2 XP_011533845.1 9, 10 3564
          XM_011535544.2 XP_011533846.1 7, 8 1748
          XM_011535545.2 XP_011533847.1 7, 8 1637
          XM_011535549.2 XP_011533851.1 4, 5 750
          XM_017010376.1 XP_016865865.1 8, 9 4186
          XM_017010377.1 XP_016865866.1 9, 10 4245
          XM_017010378.1 XP_016865867.1 8, 9 1697
          XM_017010379.1 XP_016865868.1 8, 9 1731
          XM_017010380.1 XP_016865869.1 7, 8 4055
          XM_017010381.1 XP_016865870.1 7, 8 1483
          XM_017010382.1 XP_016865871.1 5, 6 803
          XM_017010383.1 XP_016865872.1 4, 5 1108
          GenBank mRNA AB307713.1 - 6, 7 1369
          AF258449.1 - 3, 4 935
          AF258450.1 - 2, 3 818
          AF258451.1 - 3, 4 697
          AK293019.1 - 7, 8 1552
          AK304833.1 - 7, 8 1410
          AK313644.1 - 7, 8 1561
          BC128573.1 - 6, 7 1474 40128594
          BC128574.1 - 6, 7 1474 40128595
          FJ147552.1 - 4, 5 250
          FJ169502.1 - 3, 4 359
          FJ169503.1 - 4, 5 309
          GQ411258.1 - 4, 5 454
          JF810888.1 - 6, 7 1369
          LC120329.1 - 6, 7 1578
          M12674.1 - 6, 7 1661
          U47678.1 - 1369
          X03635.1 - 6, 7 1729
          Z75126.1 - 3, 4 312

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_012689, XM_008758703, XM_006227832, XM_008758704, X61098, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          antral ovarian follicle growth
          osteoblast development
          chromatin remodeling
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          transcription initiation from RNA polymerase II promoter
          signal transduction
          phospholipase C-activating G-protein coupled receptor signaling pathway
          positive regulation of cytosolic calcium ion concentration
          androgen metabolic process
          negative regulation of gene expression
          positive regulation of phospholipase C activity
          intracellular steroid hormone receptor signaling pathway
          intracellular estrogen receptor signaling pathway
          response to estradiol
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of sequence-specific DNA binding transcription factor activity
          regulation of neuron apoptotic process
          response to estrogen
          positive regulation of epidermal growth factor receptor signaling pathway
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of glucose import
          decidualization
          positive regulation of fibroblast proliferation
          negative regulation of smooth muscle cell proliferation
          positive regulation of epithelial cell proliferation
          positive regulation of sequence-specific DNA binding transcription factor activity
          Sertoli cell development
          Sertoli cell proliferation
          uterus development
          vagina development
          prostate epithelial cord elongation
          prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
          regulation of branching involved in prostate gland morphogenesis
          mammary gland branching involved in pregnancy
          mammary gland alveolus development
          epithelial cell proliferation involved in mammary gland duct elongation
          positive regulation of ERK1 and ERK2 cascade
          protein localization to chromatin
          cellular response to estrogen stimulus
          cellular response to estradiol stimulus
          negative regulation of triglyceride metabolic process
          negative regulation of neuron death
          negative regulation of production of miRNAs involved in gene silencing by miRNA
          baculum development
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          core promoter sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          transcription coactivator binding
          chromatin binding
          transcription factor activity, sequence-specific DNA binding
          steroid hormone receptor activity
          steroid binding
          protein binding
          beta-catenin binding
          transcription factor binding
          zinc ion binding
          enzyme binding
          nitric-oxide synthase regulator activity
          estrogen receptor activity
          type 1 metabotropic glutamate receptor binding
          protein complex binding
          estrogen response element binding
          phosphatidylinositol 3-kinase regulatory subunit binding
          RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
          hormone binding
          identical protein binding
          ATPase binding

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