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          System Message

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          LOADING ...
          See other FADD SIRNA Assays ›
          Gene Symbol:
          FADD
          Gene Name:
          Fas associated via death domain
          Gene Aliases:
          GIG3, MORT1
          Chromosome Location:
          Chr.11: 70203163 - 70207402 on Build GRCh38
          UniGene ID:
          Hs.86131
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s228425

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
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          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: FADD
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_003824.3 NP_003815.1 2 1802
          GenBank mRNA BC000334.2 - 2 1653 2822581
          BC025733.1 - 2 1629
          X84709.1 - 2 1650

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          positive regulation of T cell mediated cytotoxicity
          positive regulation of adaptive immune response
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          cell surface receptor signaling pathway
          extrinsic apoptotic signaling pathway via death domain receptors
          positive regulation of interferon-gamma production
          positive regulation of interleukin-8 production
          positive regulation of tumor necrosis factor production
          T cell differentiation in thymus
          TRIF-dependent toll-like receptor signaling pathway
          TRAIL-activated apoptotic signaling pathway
          positive regulation of activated T cell proliferation
          T cell homeostasis
          positive regulation of apoptotic process
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          innate immune response
          positive regulation of macrophage differentiation
          positive regulation of proteolysis
          positive regulation of transcription from RNA polymerase II promoter
          lymph node development
          spleen development
          thymus development
          protein heterooligomerization
          defense response to virus
          positive regulation of type I interferon-mediated signaling pathway
          negative regulation of necroptotic process
          negative regulation of activation-induced cell death of T cells
          cellular response to mechanical stimulus
          death-inducing signaling complex assembly
          motor neuron apoptotic process
          apoptotic signaling pathway
          extrinsic apoptotic signaling pathway
          extrinsic apoptotic signaling pathway in absence of ligand
          activation of cysteine-type endopeptidase activity
          activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
          necroptotic signaling pathway
          regulation of extrinsic apoptotic signaling pathway via death domain receptors
          negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
          positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
          positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
          positive regulation of extrinsic apoptotic signaling pathway
          protease binding
          death receptor binding
          tumor necrosis factor receptor binding
          protein binding
          protein complex binding
          tumor necrosis factor receptor superfamily binding
          death effector domain binding
          identical protein binding
          caspase binding

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