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          System Message

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          LOADING ...
          See other PYCARD SIRNA Assays ›
          Gene Symbol:
          PYCARD
          Gene Name:
          PYD and CARD domain containing
          Gene Aliases:
          ASC, CARD5, TMS, TMS-1, TMS1
          Chromosome Location:
          Chr.16: 31201486 - 31202776 on Build GRCh38
          UniGene ID:
          Hs.499094
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s26508

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PYCARD
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_013258.4 NP_037390.2 3 520
          NM_145182.2 NP_660183.1 2 463
          GenBank mRNA AB023416.2 - 3 520
          AF184073.1 - 3 508
          AF255794.1 - 2 451
          AF310103.1 - 3 434
          AF384665.1 - 3 487
          AK000211.1 - 3 472
          AK314422.1 - 3 512
          BC004470.2 - 4 490 3678925
          BC013569.1 - 3 427

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          myeloid dendritic cell activation
          activation of innate immune response
          myeloid dendritic cell activation involved in immune response
          positive regulation of antigen processing and presentation of peptide antigen via MHC class II
          positive regulation of adaptive immune response
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          inflammatory response
          signal transduction
          regulation of tumor necrosis factor-mediated signaling pathway
          positive regulation of actin filament polymerization
          regulation of protein stability
          negative regulation of NF-kappaB transcription factor activity
          negative regulation of interferon-beta production
          positive regulation of interferon-gamma production
          positive regulation of interleukin-6 production
          positive regulation of tumor necrosis factor production
          tumor necrosis factor-mediated signaling pathway
          positive regulation of activated T cell proliferation
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          positive regulation of apoptotic process
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
          macropinocytosis
          innate immune response
          positive regulation of JNK cascade
          positive regulation of interleukin-1 beta secretion
          positive regulation of phagocytosis
          defense response to Gram-negative bacterium
          positive regulation of T cell activation
          positive regulation of sequence-specific DNA binding transcription factor activity
          positive regulation of NF-kappaB transcription factor activity
          defense response to virus
          positive regulation of ERK1 and ERK2 cascade
          cellular response to lipopolysaccharide
          cellular response to interleukin-1
          cellular response to tumor necrosis factor
          negative regulation of protein serine/threonine kinase activity
          intrinsic apoptotic signaling pathway by p53 class mediator
          positive regulation of chemokine secretion
          positive regulation of release of cytochrome c from mitochondria
          positive regulation of T cell migration
          positive regulation of interleukin-8 secretion
          positive regulation of interleukin-6 secretion
          positive regulation of cysteine-type endopeptidase activity
          positive regulation of interleukin-10 secretion
          positive regulation of extrinsic apoptotic signaling pathway
          regulation of intrinsic apoptotic signaling pathway
          protease binding
          interleukin-6 receptor binding
          protein binding
          tropomyosin binding
          cysteine-type endopeptidase activator activity involved in apoptotic process
          myosin I binding
          enzyme binding
          Pyrin domain binding
          identical protein binding
          protein homodimerization activity
          BMP receptor binding
          cysteine-type endopeptidase activity involved in apoptotic process

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