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          System Message

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          LOADING ...
          See other ESR1 SIRNA Assays ›
          Gene Symbol:
          ESR1
          Gene Name:
          estrogen receptor 1
          Gene Aliases:
          ER, ESR, ESRA, ESTRR, Era, NR3A1
          Chromosome Location:
          Chr.6: 151654148 - 152103274 on Build GRCh38
          UniGene ID:
          Hs.208124
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s4823

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ESR1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000125.3 NP_000116.2 6 1533
          NM_001122740.1 NP_001116212.1 7 1560
          NM_001122741.1 NP_001116213.1 7 1517
          NM_001122742.1 NP_001116214.1 8 1669
          NM_001291230.1 NP_001278159.1 7 1523
          NM_001291241.1 NP_001278170.1 7 1514
          NM_001328100.1 NP_001315029.1 6 1012
          XM_006715374.3 XP_006715437.1 8 1669
          XM_006715375.3 XP_006715438.1 6 1666
          XM_011535543.2 XP_011533845.1 9 3494
          XM_011535544.2 XP_011533846.1 7 1678
          XM_011535545.2 XP_011533847.1 7 1567
          XM_011535547.2 XP_011533849.1 8 1669
          XM_011535549.2 XP_011533851.1 4 680
          XM_017010376.1 XP_016865865.1 8 4116
          XM_017010377.1 XP_016865866.1 9 4175
          XM_017010378.1 XP_016865867.1 8 1627
          XM_017010379.1 XP_016865868.1 8 1661
          XM_017010380.1 XP_016865869.1 7 3985
          XM_017010381.1 XP_016865870.1 7 1413
          XM_017010382.1 XP_016865871.1 5 733
          XM_017010383.1 XP_016865872.1 4 1038
          GenBank mRNA AB307713.1 - 6 1299
          AF258449.1 - 3 865
          AF258450.1 - 2 748
          AF258451.1 - 3 627
          AK293019.1 - 7 1482
          AK304833.1 - 7 1340
          AK311064.1 - 1 73
          AK313644.1 - 7 1491
          BC128573.1 - 6 1404 40128594
          BC128574.1 - 6 1404 40128595
          BX640939.1 - 6 1013
          FJ169502.1 - 3 289
          FJ169503.1 - 4 239
          FJ668387.1 - 3 245
          FJ712305.1 - 3 219
          FJ712307.1 - 5 565
          GQ411258.1 - 4 384
          JF810888.1 - 6 1299
          LC120329.1 - 6 1508
          LC120330.1 - 6 1369
          M12674.1 - 6 1591
          U47678.1 - 1299
          X03635.1 - 6 1659
          Z75126.1 - 3 242

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          antral ovarian follicle growth
          osteoblast development
          chromatin remodeling
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          transcription initiation from RNA polymerase II promoter
          signal transduction
          phospholipase C-activating G-protein coupled receptor signaling pathway
          positive regulation of cytosolic calcium ion concentration
          androgen metabolic process
          negative regulation of gene expression
          positive regulation of phospholipase C activity
          intracellular steroid hormone receptor signaling pathway
          intracellular estrogen receptor signaling pathway
          response to estradiol
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of sequence-specific DNA binding transcription factor activity
          regulation of neuron apoptotic process
          response to estrogen
          positive regulation of epidermal growth factor receptor signaling pathway
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of glucose import
          decidualization
          positive regulation of fibroblast proliferation
          negative regulation of smooth muscle cell proliferation
          positive regulation of epithelial cell proliferation
          positive regulation of sequence-specific DNA binding transcription factor activity
          Sertoli cell development
          Sertoli cell proliferation
          uterus development
          vagina development
          prostate epithelial cord elongation
          prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
          regulation of branching involved in prostate gland morphogenesis
          mammary gland branching involved in pregnancy
          mammary gland alveolus development
          epithelial cell proliferation involved in mammary gland duct elongation
          positive regulation of ERK1 and ERK2 cascade
          protein localization to chromatin
          cellular response to estrogen stimulus
          cellular response to estradiol stimulus
          negative regulation of triglyceride metabolic process
          negative regulation of neuron death
          negative regulation of production of miRNAs involved in gene silencing by miRNA
          baculum development
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          core promoter sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          transcription coactivator binding
          chromatin binding
          transcription factor activity, sequence-specific DNA binding
          steroid hormone receptor activity
          steroid binding
          protein binding
          beta-catenin binding
          transcription factor binding
          zinc ion binding
          enzyme binding
          nitric-oxide synthase regulator activity
          estrogen receptor activity
          type 1 metabotropic glutamate receptor binding
          protein complex binding
          estrogen response element binding
          phosphatidylinositol 3-kinase regulatory subunit binding
          RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
          hormone binding
          identical protein binding
          ATPase binding

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