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          System Message

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          See other EP300 SIRNA Assays ›
          Gene Symbol:
          EP300 MTO1
          Gene Name:
          E1A binding protein p300
          mitochondrial tRNA translation optimization 1
          Gene Aliases:
          KAT3B, RSTS2, p300
          CGI-02, COXPD10
          Chromosome Location:
          Chr.22: 41092610 - 41180077 on Build GRCh38
          Chromosome Location:
          Chr.6: 73461727 - 73501456 on Build GRCh38
          UniGene ID:
          Hs.517517
          Hs.347614
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          -
          siRNA ID s534248

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: EP300
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001429.3 NP_001420.2 23 4244
          XM_006724165.3 XP_006724228.1 22 3866
          GenBank mRNA BC053889.1 - 23 4212
          U01877.1 - 23 5048
          Gene Symbol: MTO1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          GenBank mRNA DN993156.1 - 1 70

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: CD348567, BC150681, BC144976, AK040384, CB245766, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          response to hypoxia
          somitogenesis
          liver development
          positive regulation of protein phosphorylation
          stimulatory C-type lectin receptor signaling pathway
          transcription-coupled nucleotide-excision repair
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          protein acetylation
          internal protein amino acid acetylation
          apoptotic process
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
          Notch signaling pathway
          nervous system development
          heart development
          skeletal muscle tissue development
          memory
          circadian rhythm
          organ morphogenesis
          regulation of autophagy
          positive regulation of glycoprotein biosynthetic process
          macrophage derived foam cell differentiation
          positive regulation of cell death
          positive regulation of muscle atrophy
          viral process
          N-terminal peptidyl-lysine acetylation
          internal peptidyl-lysine acetylation
          B cell differentiation
          platelet formation
          lung development
          response to cobalt ion
          positive regulation of protein binding
          positive regulation of type I interferon production
          positive regulation of collagen biosynthetic process
          positive regulation of protein import into nucleus, translocation
          response to tumor necrosis factor
          cellular response to UV
          positive regulation of histone acetylation
          cellular response to drug
          megakaryocyte development
          cellular response to trichostatin A
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
          positive regulation of DNA binding
          protein kinase B signaling
          response to estrogen
          positive regulation by host of viral transcription
          histone H3 acetylation
          histone H4 acetylation
          histone H2B acetylation
          fat cell differentiation
          response to ethanol
          positive regulation of translation
          positive regulation of axon extension
          positive regulation of cell size
          positive regulation of gene expression, epigenetic
          positive regulation of proteolysis
          positive regulation of transcription from RNA polymerase II promoter
          digestive tract development
          positive regulation of protein secretion
          protein stabilization
          positive regulation of sequence-specific DNA binding transcription factor activity
          response to calcium ion
          regulation of cell cycle
          regulation of angiotensin metabolic process
          positive regulation of sarcomere organization
          regulation of androgen receptor signaling pathway
          regulation of transcription from RNA polymerase II promoter in response to hypoxia
          protein-DNA complex assembly
          cellular response to hydrogen peroxide
          response to fatty acid
          cellular response to retinoic acid
          cellular response to cAMP
          cellular response to glucose stimulus
          cellular response to mineralocorticoid stimulus
          cellular response to dexamethasone stimulus
          regulation of tubulin deacetylation
          regulation of cellular response to heat
          regulation of signal transduction by p53 class mediator
          beta-catenin-TCF complex assembly
          cellular response to nerve growth factor stimulus
          negative regulation of miRNA metabolic process
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          RNA polymerase II core promoter sequence-specific DNA binding
          core promoter binding
          RNA polymerase II activating transcription factor binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          p53 binding
          DNA binding
          chromatin binding
          damaged DNA binding
          transcription coactivator activity
          histone acetyltransferase activity
          lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
          protein binding
          beta-catenin binding
          protein C-terminus binding
          transcription factor binding
          zinc ion binding
          acetyltransferase activity
          transferase activity, transferring acyl groups
          chromatin DNA binding
          protein complex binding
          activating transcription factor binding
          peptide N-acetyltransferase activity
          nuclear hormone receptor binding
          glucocorticoid receptor binding
          peroxisome proliferator activated receptor binding
          bHLH transcription factor binding
          SMAD binding
          androgen receptor binding
          mitogen-activated protein kinase binding
          NF-kappaB binding
          pre-mRNA intronic binding
          protein antigen binding

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