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          System Message

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          See other FOXP3 SIRNA Assays ›
          Gene Symbol:
          Foxp3
          Gene Name:
          forkhead box P3
          Gene Aliases:
          JM2, scurfin, sf
          Chromosome Location:
          Chr.X: 7579676 - 7595243 on Build GRCm38
          UniGene ID:
          Mm.182291
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID s73596

          Purification
          Size
          Availability Made To Order
          Catalog # 4390771
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Foxp3
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001199347.1 NP_001186276.1 14 1578
          NM_001199348.1 NP_001186277.1 13 1436
          NM_054039.2 NP_473380.1 13 1511
          GenBank mRNA AF277991.1 - 13 1436
          AF277992.1 - 13 1494
          AK157447.1 - 14 1579
          AY357712.1 - 12 1294
          AY357713.1 - 12 1294
          BC132333.1 - 12 1282 40130610
          BC132335.1 - 12 1282 40130612
          DQ387959.1 - 14 1578
          KF471319.1 - 12 1278

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_001108250, XM_006256731, AB232989, AB232988, AB232990.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          B cell homeostasis
          cytokine production
          myeloid cell homeostasis
          CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
          CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment
          T cell mediated immunity
          tolerance induction
          tolerance induction to self antigen
          regulation of immunoglobulin production
          positive regulation of T cell tolerance induction
          regulation of T cell anergy
          positive regulation of T cell anergy
          negative regulation of chronic inflammatory response
          negative regulation of T cell cytokine production
          positive regulation of peripheral T cell tolerance induction
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          transcription from RNA polymerase II promoter
          negative regulation of cell proliferation
          anatomical structure morphogenesis
          positive regulation of gene expression
          negative regulation of histone deacetylation
          negative regulation of NF-kappaB transcription factor activity
          negative regulation of interferon-gamma production
          negative regulation of interleukin-10 production
          negative regulation of interleukin-17 production
          negative regulation of interleukin-2 production
          negative regulation of interleukin-4 production
          negative regulation of interleukin-5 production
          negative regulation of interleukin-6 production
          negative regulation of tumor necrosis factor production
          positive regulation of interleukin-4 production
          negative regulation of CREB transcription factor activity
          positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
          positive regulation of transforming growth factor beta1 production
          positive regulation of immature T cell proliferation in thymus
          positive regulation of histone acetylation
          negative regulation of histone acetylation
          negative regulation of cytokine biosynthetic process
          T cell activation
          negative regulation of T cell proliferation
          negative regulation of sequence-specific DNA binding transcription factor activity
          regulatory T cell differentiation
          negative regulation of interferon-gamma biosynthetic process
          negative regulation of interleukin-2 biosynthetic process
          positive regulation of regulatory T cell differentiation
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of isotype switching to IgE isotypes
          regulation of isotype switching to IgG isotypes
          negative regulation of lymphocyte proliferation
          negative regulation of cytokine secretion
          negative regulation of inflammatory response
          negative regulation of immune response
          T cell receptor signaling pathway
          negative regulation of T-helper 17 cell differentiation
          core promoter binding
          nucleic acid binding
          DNA binding
          transcription factor activity, sequence-specific DNA binding
          transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
          transcription corepressor activity
          protein binding
          histone acetyltransferase binding
          protein homodimerization activity
          histone deacetylase binding
          sequence-specific DNA binding
          metal ion binding
          NFAT protein binding

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