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          System Message

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          LOADING ...
          See other THBS1 SIRNA Assays ›
          Gene Symbol:
          Thbs1
          Gene Name:
          thrombospondin 1
          Gene Aliases:
          TSP-1, TSP1, Thbs-1, tbsp1
          Chromosome Location:
          Chr.2: 118111890 - 118127133 on Build GRCm38
          UniGene ID:
          Mm.4159
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID s75096

          Purification
          Size
          Availability Made To Order
          Catalog # 4390771
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Thbs1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_011580.3 NP_035710.2 6 1174
          GenBank mRNA AK080686.1 - 6 1209
          AK145202.1 - 6 1204
          AK163092.1 - 6 1201
          BC020435.1 - 6 1182
          BC042422.1 - 6 1176 4018176
          BC050917.1 - 6 1174 6405710
          M87276.1 - 6 1200

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_001013062, AF309630.

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPK activity
          negative regulation of endothelial cell proliferation
          negative regulation of cell-matrix adhesion
          sprouting angiogenesis
          negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
          negative regulation of dendritic cell antigen processing and presentation
          outflow tract morphogenesis
          endocardial cushion development
          growth plate cartilage development
          inflammatory response
          response to unfolded protein
          cell cycle arrest
          cell adhesion
          response to mechanical stimulus
          response to glucose
          positive regulation of endothelial cell migration
          negative regulation of endothelial cell migration
          negative regulation of plasma membrane long-chain fatty acid transport
          negative regulation of nitric oxide mediated signal transduction
          negative regulation of cGMP-mediated signaling
          negative regulation of plasminogen activation
          positive regulation of macrophage chemotaxis
          positive regulation of fibroblast migration
          positive regulation of cell-substrate adhesion
          cell migration
          negative regulation of angiogenesis
          peptide cross-linking
          positive regulation of blood coagulation
          positive regulation of cell migration
          positive regulation of transforming growth factor beta receptor signaling pathway
          regulation of cGMP metabolic process
          response to magnesium ion
          negative regulation of interleukin-12 production
          response to endoplasmic reticulum stress
          negative regulation of fibroblast growth factor receptor signaling pathway
          positive regulation of phosphorylation
          positive regulation of tumor necrosis factor biosynthetic process
          positive regulation of macrophage activation
          negative regulation of apoptotic process
          negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
          positive regulation of blood vessel endothelial cell migration
          negative regulation of blood vessel endothelial cell migration
          engulfment of apoptotic cell
          positive regulation of translation
          positive regulation of angiogenesis
          behavioral response to pain
          blood vessel morphogenesis
          positive regulation of chemotaxis
          response to calcium ion
          positive regulation of protein kinase B signaling
          negative regulation of fibrinolysis
          positive regulation of transforming growth factor beta production
          cellular response to nitric oxide
          positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
          positive regulation of endothelial cell apoptotic process
          positive regulation of reactive oxygen species metabolic process
          negative regulation of endothelial cell chemotaxis
          phosphatidylserine binding
          fibronectin binding
          integrin binding
          calcium ion binding
          protein binding
          heparin binding
          fibroblast growth factor binding
          low-density lipoprotein particle binding
          laminin binding
          transforming growth factor beta binding
          extracellular matrix binding
          fibrinogen binding
          collagen V binding

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          Host server : magellan-search-74594944d-pk6zc:80/100.66.130.62:80.
          git-commit: ab2b2261c2971e97b1ae408e3ad10520b8413932
          git-url: https://github.com/thermofisher/magellan-search
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