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          System Message

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          See other ACVRL1 SIRNA Assays ›
          Gene Symbol:
          ACVRL1
          Gene Name:
          activin A receptor like type 1
          Gene Aliases:
          ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
          Chromosome Location:
          Chr.12: 51906913 - 51923361 on Build GRCh38
          UniGene ID:
          Hs.591026
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s988

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ACVRL1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000020.2 NP_000011.2 8 1443
          NM_001077401.1 NP_001070869.1 7 1306
          XM_005269235.2 XP_005269292.1 9 1445
          XM_011539008.1 XP_011537310.1 5 989
          GenBank mRNA AK298493.1 - 5 470
          AK300619.1 - 3 424
          AK303331.1 - 4 701
          BC042637.1 - 7 1192 5179243
          KU177888.1 - 7 1160
          KU177889.1 - 5 848
          L17075.1 - 7 1251
          Z22533.1 - 8 1442

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          angiogenesis
          in utero embryonic development
          regulation of endothelial cell proliferation
          negative regulation of endothelial cell proliferation
          positive regulation of endothelial cell proliferation
          lymphangiogenesis
          blood vessel maturation
          blood vessel remodeling
          blood vessel endothelial cell proliferation involved in sprouting angiogenesis
          endocardial cushion morphogenesis
          regulation of DNA replication
          regulation of transcription, DNA-templated
          protein phosphorylation
          negative regulation of cell adhesion
          signal transduction
          transforming growth factor beta receptor signaling pathway
          blood circulation
          regulation of blood pressure
          negative regulation of cell proliferation
          negative regulation of endothelial cell migration
          negative regulation of gene expression
          positive regulation of pathway-restricted SMAD protein phosphorylation
          signal transduction by protein phosphorylation
          negative regulation of cell growth
          negative regulation of cell migration
          BMP signaling pathway
          positive regulation of BMP signaling pathway
          positive regulation of chondrocyte differentiation
          activin receptor signaling pathway
          wound healing, spreading of epidermal cells
          dorsal aorta morphogenesis
          regulation of blood vessel endothelial cell migration
          negative regulation of blood vessel endothelial cell migration
          negative regulation of endothelial cell differentiation
          positive regulation of endothelial cell differentiation
          positive regulation of angiogenesis
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          protein heterooligomerization
          negative regulation of focal adhesion assembly
          lymphatic endothelial cell differentiation
          artery development
          venous blood vessel development
          endothelial tube morphogenesis
          retina vasculature development in camera-type eye
          cellular response to transforming growth factor beta stimulus
          cellular response to BMP stimulus
          endocardial cushion to mesenchymal transition
          negative regulation of DNA biosynthetic process
          protein serine/threonine kinase activity
          transmembrane receptor protein serine/threonine kinase activity
          receptor signaling protein serine/threonine kinase activity
          transforming growth factor beta-activated receptor activity
          transforming growth factor beta receptor activity, type I
          protein binding
          ATP binding
          activin receptor activity, type I
          protein kinase binding
          SMAD binding
          metal ion binding
          activin binding
          transforming growth factor beta binding
          BMP receptor activity

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