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Invitrogen
Human ABCA9 (aa 442-470) Control Fragment Recombinant Protein
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Product Details
RP-101389
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
FWFQHGRANHVVLENETDSDPTPNDCFEP
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (62%), Rat (62%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63027. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
ABCA9 (ATP-binding cassette, sub-family A (ABC1), member 9) is a 1,624 amino acid protein belonging to the ABC transporter superfamily and the ABCA family. The ABC1 subfamily is the only major ABC subfamily exclusive to multicellular eukaryotes. Ubiquitously expressed, with high expression in heart, brain and fetal tissues, ABCA9 is a multi-pass membrane protein that contains two ABC transporter domains and exists as five alternatively spliced isoforms. ABCA9 exhibits membrane subcellular localization and may play a role in monocyte differentiation and lipid homeostasis. ABCA9 is up-regulated during monocyte differentiation into macrophages and down-regulated by cholesterol loading of macrophages. Spanning 85 kb, ABCA9 contains 39 exons, with a non-coding first exon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-binding cassette A9; ATP-binding cassette sub-family A member 9; ATP-binding cassette, sub-family A (ABC1), member 9; DKFZp686F2450; MGC75415
Gene Aliases: ABCA9; EST640918
UniProt ID: (Human) Q8IUA7
Entrez Gene ID: (Human) 10350
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