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Invitrogen
Human ANO5 (aa 335-381) Control Fragment Recombinant Protein
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Product Details
RP-97462
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
NTSSTEICDPEIGGQMIMCPLCDQVCDYWRLNSTCLASKFSHLFDNE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63619. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Ano5 does not exhibit calcium-activated chloride channel (CaCC) activity. The Ano5 gene encodes a member of the anoctamin family of transmembrane proteins. The Ano5 protein is likely a calcium activated chloride channel. Mutations in the Ano5 gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described for Ano5. Diseases associated with ANO5 include Gnathodiaphyseal Dysplasia and Miyoshi Muscular Dystrophy 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Anoctamin-5; Gnathodiaphyseal dysplasia 1 protein; integral membrane protein GDD1; Transmembrane protein 16E
Gene Aliases: ANO5; GDD1; LGMD2L; TMEM16E
UniProt ID: (Human) Q75V66
Entrez Gene ID: (Human) 203859
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