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          • Proteins & Peptides ›
          • AP3M1 Proteins

          Invitrogen

          Human AP3M1 (aa 11-36) Control Fragment Recombinant Protein

          View all (3) AP3M1 proteins

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          Cite Human AP3M1 (aa 11-36) Control Fragment Recombinant Protein

          Product Details

          RP-103707

          Applications
          Tested Dilution
          Publications

          Control (Ctrl)

          Assay-dependent
          -

          Blocking Assay (BLOCK)

          Assay-dependent
          -
          Product Specifications

          Species

          Human

          Expression System

          E. coli

          Amino acid sequence

          SGDIFLEKHWKSVVSQSVCDYFFEAQ

          Tag

          His-ABP-tag

          Class

          Recombinant

          Type

          Protein

          Purity

          >80% by SDS-PAGE and Coomassie blue staining

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          ≥5.0 mg/mL

          Purification

          purified

          Storage buffer

          1M urea/PBS, pH 7.4

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Product Specific Information

          Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).

          This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61040. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

          Target Information

          The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: adapter-related protein complex 3 mu-1 subunit; Adaptor-related protein complex 3 subunit mu-1; AP-3 adapter complex mu3A subunit; AP-3 adaptor complex mu3A subunit; AP-3 complex subunit mu-1; ap3; clathrin adaptor complex AP3, mu-3A subunit; Mu-adaptin 3A; Mu3A-adaptin

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          Gene Aliases: AP3M1

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          UniProt ID: (Human) Q9Y2T2

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          Entrez Gene ID: (Human) 26985

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          It has to be done as per old AB suggested Products section.
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