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Highest antigen sequence indentity to the following orthologs: Mouse (59%), Rat (59%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52201. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cell migration, cell proliferation, tissue maintenance and tumorigenesis, and they also function in signal transduction and the maintenance of overall cell structure. ARMCX2 (armadillo repeat containing, X-linked 2), also known as ALEX2, is a 632 amino acid single-pass membrane protein that contains three ARM repeats and is highly expressed in testis, brain, ovary, heart, colon, spleen and prostate, where it is thought to play a role in tumor suppression. The gene encoding ARMCX2 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1, 000 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARM protein lost in epithelial cancers on chromosome X 2; armadillo repeat protein ALEX2; Armadillo repeat-containing X-linked protein 2; Protein ALEX2
Gene Aliases: ALEX2; ARMCX2; GASP9; KIAA0512
UniProt ID: (Human) Q7L311
Entrez Gene ID: (Human) 9823
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