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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (60%), Rat (60%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53249. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ASGR2 is a cell surface receptor that binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ANCO-2; ANCO1; ASGP-R 2; Asialoglycoprotein receptor 2; C-type lectin domain family 4 member H2; GAC-1; HBxAg-binding protein; Hepatic lectin H2; HL-2; Nbla00144
Gene Aliases: ASGP-R2; ASGPR2; ASGR2; CLEC4H2; HBXBP; HL-2
UniProt ID: (Human) P07307
Entrez Gene ID: (Human) 433
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