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Invitrogen
Human AZGP1 (aa 24-145) Control Fragment Recombinant Protein
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Product Details
RP-100376
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
QDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYI
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (61%), Rat (61%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52951. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Alpha-2-glycoprotein 1, zinc-binding (AZGP1) is a gene encoding a protein that belongs to the immunoglobulin superfamily. This protein is abundant in various body fluids, such as blood plasma and milk, and is involved in lipid mobilization. AZGP1 is expressed in numerous tissues, including the liver, prostate, and adipose tissue, where it plays a significant role in the regulation of lipid metabolism and adipocyte function. It acts as an adipokine, influencing the breakdown and mobilization of fats, thereby contributing to energy homeostasis. In cancer research, AZGP1 has been highlighted for its potential as a prognostic biomarker, particularly in prostate and breast cancer, where lower expression levels are often associated with poor prognosis. Recent studies have also linked AZGP1 to cachexia, an extreme form of weight loss and muscle wasting, by promoting lipid mobilization in adipose tissue and influencing systemic catabolic states. Due to its multifaceted roles in lipid metabolism and disease processes, AZGP1 is considered a promising target for therapeutic interventions in metabolic and cancer-related disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-2-glycoprotein, zinc; testicular tissue protein Li 227; Zinc a 2 glycoprotein; Zinc a2glycoprotein; Zinc alpha2glycoprotein; Zinc α 2 glycoprotein; Zinc α2glycoprotein; Zinc-alpha-2-glycoprotein; Zn a 2 glycoprotein; Zn a 2 GP; Zn alpha 2 glycoprotein; Zn alpha 2 GP; Zn α 2 glycoprotein; Zn α 2 GP; zn-alpha-2-glycoprotein; Zn-alpha-2-GP; Zn-alpha2-glycoprotein
Gene Aliases: AZGP1; ZA2G; ZAG; ZNGP1
UniProt ID: (Human) P25311
Entrez Gene ID: (Human) 563
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