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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64107. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adenylate kinase 3; Adenylate kinase 3 alpha-like 1; adenylate kinase 6, adenylate kinase 3 like 1; Adenylate kinase isozyme 3; AK3; AK4; GTP:AMP phosphotransferase AK3, mitochondrial; GTP:AMP phosphotransferase, mitochondrial
Gene Aliases: AK3; AK3L1; AK6; AKL3L; AKL3L1; FIX
UniProt ID: (Human) Q9UIJ7
Entrez Gene ID: (Human) 50808
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