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Invitrogen
Human BRPF1 (aa 752-859) Control Fragment Recombinant Protein
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Product Details
RP-100748
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
SLAGDEATHHTEDAAEEERLVLLENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPSSRGSLTPHPAACDKDGQTD
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51909. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
BRPF1 (peregrin) is a component of the MOZ/MORF complex. This complex has histone H3 acetyltransferase activity. BRPF1 preferentially mediates histone H3-K23 acetylation and positively regulates the transcription of RUNX1 and RUNX2. Mutations affecting the gene can result in intellectual developmental disorder with dysmorphic facies and ptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bromodomain and PHD finger-containing protein 1; bromodomain-containing protein, 140kD; Peregrin; Protein Br140
Gene Aliases: BR140; BRPF1
UniProt ID: (Human) P55201
Entrez Gene ID: (Human) 7862
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