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Invitrogen
Human C1orf165 (aa 113-195) Control Fragment Recombinant Protein
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Product Details
RP-94362
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
DLQLRHIKRPEGRKPSEVAHKSIEAVVARLEKQNGLSLGHSTCPEEVFVEASPGTEDMDSLEDAVVPRALYEELLRNYQQQQE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63507. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
C1orf165, also known as CFAP299 (Cilia and Flagella Associated Protein 299), is located on chromosome 1 and encodes a protein that is implicated in ciliary function and structure. CFAP299 is essential for the proper assembly and motility of cilia and flagella, structures that are vital for various cellular processes, including cell motility, fluid movement, and signal transduction. Mutations in CFAP299 have been linked to primary ciliary dyskinesia (PCD), which is characterized by chronic respiratory tract infections, abnormal positioning of internal organs (situs inversus), and infertility due to defective cilia and flagella movement. The protein has been shown to interact with other ciliary proteins and play a role in the regulation of dynein arms and microtubule structures necessary for ciliary beating.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BEN domain-containing protein 5
Gene Aliases: BEND5; C1orf165
UniProt ID: (Human) Q7L4P6
Entrez Gene ID: (Human) 79656
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