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Invitrogen
Human CALHM2 (aa 124-185) Control Fragment Recombinant Protein
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Product Details
RP-91152
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
RGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQ
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53219. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
CALHM2, also named as FAM26B, is a pore-forming subunit of a voltage-gated ion channel. It is a critical ATP-releasing channel that modulates neural activity and as a potential risk factor of depression. There are three isoforms of CALHM2 with calculated MW 36 kDa, 24 kDa and 22 kDa. It is about 32-36 kDa in western blot with membrane protein extracted lysate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcium homeostasis modulator protein 2; family with sequence similarity 26, member B; Protein FAM26B
Gene Aliases: CALHM2; FAM26B
UniProt ID: (Human) Q9HA72
Entrez Gene ID: (Human) 51063
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