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Invitrogen
Human CCDC90B (aa 117-230) Control Fragment Recombinant Protein
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Product Details
RP-90270
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
AHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52795. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
CCDC90B (Coiled-Coil Domain-Containing 90B), also known as MCUR1 (Mitochondrial Calcium Uniporter Regulator 1), is a gene located on chromosome 16p13.3 that encodes a protein involved in mitochondrial function. MCUR1 is a critical component of the mitochondrial calcium uniporter complex, which plays a vital role in regulating mitochondrial calcium uptake. Calcium uptake by mitochondria is essential for cellular metabolism, energy production, and apoptosis. MCUR1 interacts with other components of the uniporter complex to modulate the entry of calcium into the mitochondrial matrix, thereby influencing mitochondrial bioenergetics and reactive oxygen species (ROS) generation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coiled-coil domain-containing protein 90B, mitochondrial
Gene Aliases: CCDC90B; CUA003; MDS011; MDS025
UniProt ID: (Human) Q9GZT6
Entrez Gene ID: (Human) 60492
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