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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64320. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-demethoxyubiquinone 3-hydroxylase (NADH); 5-demethoxyubiquinone hydroxylase; coenzyme Q biosynthesis protein 7 homolog; coenzyme Q7 homolog, ubiquinone; COQ7 coenzyme Q, 7 homolog ubiquinone; DMQ hydroxylase; NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial; placental protein KG-20; Timing protein clk-1 homolog; Ubiquinone biosynthesis monooxygenase COQ7; ubiquinone biosynthesis protein COQ7 homolog
Gene Aliases: CAT5; CLK-1; CLK1; COQ10D8; COQ7
UniProt ID: (Human) Q99807
Entrez Gene ID: (Human) 10229
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