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Invitrogen
Human DESI1 (aa 27-82) Control Fragment Recombinant Protein
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Product Details
RP-100920
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
IMLGKQLEGIWHTSIVVHKDEFFFGSGGISSCPPGGTLLGPPDSVVDVGSTEVTEE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62786. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46. Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (PubMed:29666234). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DeSI-1; Desumoylating isopeptidase 1; desumoylating isopeptidase 2; family with sequence similarity 152, member B; Palmitoyl protein thioesterase DESI1; Polyubiquitinated substrate transporter; POST; PPPDE peptidase domain containing 2; PPPDE peptidase domain-containing protein 2; S-depalmitoylase DESI1
Gene Aliases: D15Wsu75e; DeSI-1; DESI1; DESI2; DJ347H13.4; FAM152B; PPPDE2
UniProt ID: (Human) Q6ICB0
Entrez Gene ID: (Human) 27351
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