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Invitrogen
Human DPM3 (aa 64-88) Control Fragment Recombinant Protein
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Product Details
RP-91044
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
FHDCEDAARELQSQIQEARADLARR
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53208. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dolichol-phosphate mannose synthase subunit 3; Dolichol-phosphate mannosyltransferase subunit 3; Dolichyl-phosphate beta-D-mannosyltransferase subunit 3; dolichyl-phosphate mannosyltransferase polypeptide 3; DPM synthase complex subunit 3; DPM synthase subunit 3; Mannose-P-dolichol synthase subunit 3; MGC125904; MGC125905; MGC34275; MPD synthase subunit 3; prostin 1; Prostin-1; testicular tissue protein Li 58
Gene Aliases: CDG1O; DPM3
UniProt ID: (Human) Q9P2X0
Entrez Gene ID: (Human) 54344
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