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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59376. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis. It is a holoenzyme shell (approximately 450 kDa) consisting of 24 subunits of two types, H (heavy) and L (light), and capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiologic status of the cell, the ratio of H to L subunits in ferritin can vary widely. It can be viewed not only as part of a group of iron regulatory proteins that include transferrin and the transferrin receptor, but also as a member of the protein family that orchestrates the cellular defense against stress and inflammation. Ferritin is found in the liver, spleen, kidney and heart. Only a small amount is found in the blood. The blood level of ferritin serves as an indicator of the amount of iron stored in the body.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bA379J5.3; bA555E18.1; D-aminoacyl-tRNA deacylase 1; D-tyrosyl-tRNA deacylase 1 homolog; DNA-unwinding element-binding protein B; DTD; DUE-B; Gly-tRNA(Ala) deacylase; Histidyl-tRNA synthase-related; histidyl-tRNA synthetase 2; MGC119131; MGC41905
Gene Aliases: C20orf88; DTD1; DUE-B; DUEB; HARS2; pqn-68
UniProt ID: (Human) Q8TEA8
Entrez Gene ID: (Human) 92675
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