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Invitrogen
Human Desmoglein 4 (aa 415-509) Control Fragment Recombinant Protein
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Product Details
RP-101507
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
DLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSP
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (77%), Rat (77%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63728. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Desmoglein proteins are cadherin-type cell adhesion molecules. Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, 37% with human desmoglein 2 and 50% with human desmoglein 3. A type I membrane protein of the cadherin protein family, dsg4 is expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate and skin. In the hair follicle, dsg4 is an important mediator of keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation. The human DSG4 gene is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cadherin family member 13; Desmoglein-4; Desmoglein4
Gene Aliases: CDGF13; CDHF13; DSG4; HYPT6; LAH
UniProt ID: (Human) Q86SJ6
Entrez Gene ID: (Human) 147409
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