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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82770. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Ecm29 appears to be one of three proteins which associate significantly with proteasomes. Ecm29 has been shown to enhance the stability of the proteasome. Ecm29 deletion has been shown to produce 26S proteasomes which dissociated in the absence of ATP. It was thus suggested that Ecm29 tethers the regulatory complex to the proteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ECM29 homolog, proteasome accessory protein; Ecm29 proteasome adapter and scaffold; FLJ22036; homolog of yeast Ecm29; KIAA1962; Proteasome adapter and scaffold protein ECM29; Proteasome-associated protein ECM29 homolog; RP11-386D8.2
Gene Aliases: ECM29; ECPAS; KIAA0368
UniProt ID: (Human) Q5VYK3
Entrez Gene ID: (Human) 23392
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