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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (69%), Rat (69%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61090. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
EME2 forms a heterodimer with MUS81 that functions as an XPF-type flap/fork endonuclease in DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: essential meiotic endonuclease 1 homolog 2; homolog of yeast EME1 endonuclease 2; Probable crossover junction endonuclease EME2; SLX2 structure-specific endonuclease subunit homolog B
Gene Aliases: EME2; gs125; SLX2B
UniProt ID: (Human) A4GXA9
Entrez Gene ID: (Human) 197342
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