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Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51398. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: APK1 antigen; Cytosolic ovarian carcinoma antigen 1; Ecto-NOX disulfide-thiol exchanger 2; tNOX; Tumor-associated hydroquinone oxidase
Gene Aliases: APK1; COVA1; ENOX2; tNOX
UniProt ID: (Human) Q16206
Entrez Gene ID: (Human) 10495
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