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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53619. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP, AMP, ADP, ATP and UMP are not substrates. Preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ectonucleoside triphosphate diphosphohydrolase 4; golgi luminal UDPase; Golgi UDPase; guanosine-diphosphatase like protein; lysosomal apyrase-like 1; Lysosomal apyrase-like protein of 70 kDa; NTPDase 4; UDPase; Uridine-diphosphatase
Gene Aliases: ENTPD4; KIAA0392; LALP70; LAP70; LYSAL1; NTPDase-4; UDPase
UniProt ID: (Human) Q9Y227
Entrez Gene ID: (Human) 9583
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