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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (69%), Rat (69%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140325. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
EPPIN-WFDC6 is a gene located on chromosome 20, resulting from read-through transcription between the SPINLW1 and WFDC6 genes. This gene encodes a fusion protein that exhibits functions related to both its parent genes. Structurally, EPPIN-WFDC6 includes elements from the WFDC6 gene, such as a WAP-type four-disulfide core domain, which is associated with antiprotease activity. This gene is notably expressed in the male reproductive system, particularly in the epididymis and seminal vesicles, where it plays a crucial role in sperm maturation and protection. EPPIN-WFDC6 is also involved in the regulation of proteolytic processes essential for reproductive function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cancer/testis antigen 71; CT71; Epididymal protease inhibitor; EPPIN; Protease inhibitor WAP7; Semenogelin-binding protein; Serine protease inhibitor-like with Kunitz and WAP domains 1; SPINLW1; SPINLW1-WFDC6 read-through transcript; SPINLW1-WFDC6 readthrough; WAP four-disulfide core domain protein 7; WFDC6
Gene Aliases: EPPIN; SPINLW1; SPINLW1-WFDC6; WAP7; WFDC7
UniProt ID: (Human) O95925
Entrez Gene ID: (Human) 100526773
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