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Invitrogen
Human ERAP2 (aa 659-735) Control Fragment Recombinant Protein
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Product Details
RP-102620
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
RVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVID
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (36%), Rat (36%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56955. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex class I molecules rely on aminopeptidases such as ERAP1 and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum following cleavage in the cytoplasm by tripeptidyl peptidase II.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endoplasmic reticulum aminopeptidase 2; FLJ23633; FLJ23701; FLJ23807; L-RAP; Leukocyte-derived arginine aminopeptidase
Gene Aliases: ERAP2; L-RAP; LRAP
UniProt ID: (Human) Q6P179
Entrez Gene ID: (Human) 64167
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