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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54011. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ELKS/Rab6-interacting/CAST family member 1; ERC-1; FLJ31750; MGC12974; OTTHUMP00000160633; RAB6 interacting protein 2; Rab6-interacting protein 2
Gene Aliases: Cast2; ELKS; ERC-1; ERC1; KIAA1081; RAB6IP2
UniProt ID: (Human) Q8IUD2
Entrez Gene ID: (Human) 23085
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